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PFN2 profilin 2 [ Gallus gallus (chicken) ]

Gene ID: 771904, updated on 17-Jun-2019

Summary

Symbol
PFN2provided by CGNC
Full Name
profilin 2provided by CGNC
Primary source
CGNC:7926
See related
Ensembl:ENSGALG00000054686
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PFN1; profilin-2
Orthologs

Genomic context

See PFN2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
104 current GRCg6a (GCF_000002315.5) 9 NC_006096.5 (23902667..23907847)
103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 9 NC_006096.4 (23850630..23855814)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 9 NC_006096.3 (23218003..23221938)

Chromosome 9 - NC_006096.5Genomic Context describing neighboring genes Neighboring gene atherin-like Neighboring gene TSC22 domain family member 2 Neighboring gene uncharacterized LOC107054149 Neighboring gene uncharacterized LOC107054150 Neighboring gene ring finger protein 13 Neighboring gene COMM domain containing 2

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

General protein information

Preferred Names
profilin-2
Names
profilin 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079760.1NP_001073228.1  profilin-2

    See identical proteins and their annotated locations for NP_001073228.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ719884
    UniProtKB/TrEMBL
    Q5ZL50
    Related
    ENSGALP00000073860.1, ENSGALT00000106367.1
    Conserved Domains (1) summary
    smart00392
    Location:2140
    PROF; Profilin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCg6a Primary Assembly

Genomic

  1. NC_006096.5 Reference GRCg6a Primary Assembly

    Range
    23902667..23907847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291695.2XP_015147181.1  profilin-2 isoform X1

    Conserved Domains (1) summary
    smart00392
    Location:2139
    PROF; Profilin
  2. XM_025153418.1XP_025009186.1  profilin-2 isoform X2

    Conserved Domains (1) summary
    cl00123
    Location:15117
    PROF; Profilin binds actin monomers, membrane polyphosphoinositides such as PI(4,5)P2, and poly-L-proline. Profilin can inhibit actin polymerization into F-actin by binding to monomeric actin (G-actin) and terminal F-actin subunits, but - as a regulator of the ...
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