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Csrnp3 cysteine-serine-rich nuclear protein 3 [ Mus musculus (house mouse) ]

Gene ID: 77771, updated on 23-Jun-2021

Summary

Official Symbol
Csrnp3provided by MGI
Official Full Name
cysteine-serine-rich nuclear protein 3provided by MGI
Primary source
MGI:MGI:1925021
See related
Ensembl:ENSMUSG00000044647
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CSR; Mbu1; Csnrp3; taip-2; CSRNP-3; A330102K23Rik
Expression
Biased expression in CNS E18 (RPKM 9.1), whole brain E14.5 (RPKM 8.2) and 7 other tissues See more
Orthologs
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Genomic context

See Csrnp3 in Genome Data Viewer
Location:
2; 2 C1.3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (65675628..65866958)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (65845284..66036614)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (65683824..65869603)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm777 Neighboring gene sodium channel, voltage-gated, type II, alpha Neighboring gene predicted gene, 51432 Neighboring gene predicted gene, 52514 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 3 Neighboring gene tetratricopeptide repeat domain 21B

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cysteine/serine-rich nuclear protein 3
Names
TGF-beta induced apoptosis protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290665.1NP_001277594.1  cysteine/serine-rich nuclear protein 3 isoform b

    See identical proteins and their annotated locations for NP_001277594.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks three 5' exons but contains an alternate 5' terminal exon, and it thus differs in the 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.
    Source sequence(s)
    AK158873, AL929230, AW492062
    Consensus CDS
    CCDS71060.1
    UniProtKB/Swiss-Prot
    P59055
    Related
    ENSMUSP00000135605.2, ENSMUST00000145598.9
    Conserved Domains (1) summary
    pfam16019
    Location:61278
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  2. NM_001290666.1NP_001277595.1  cysteine/serine-rich nuclear protein 3 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate exons, and it thus differs in its 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    AL929230, AW492062, BC055701, BY297754
    UniProtKB/TrEMBL
    Q7TNU4
    Conserved Domains (2) summary
    pfam16019
    Location:35180
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
    cl00310
    Location:371416
    AIRC; AIR carboxylase
  3. NM_153409.5NP_700458.3  cysteine/serine-rich nuclear protein 3 isoform a

    See identical proteins and their annotated locations for NP_700458.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Both variants 1 and 2 encode isoform a.
    Source sequence(s)
    AK039150, AL929230, BY297754, EF210820
    Consensus CDS
    CCDS16074.2
    UniProtKB/Swiss-Prot
    P59055
    Related
    ENSMUSP00000117533.2, ENSMUST00000122912.8
    Conserved Domains (1) summary
    pfam16019
    Location:73290
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  4. NM_178634.2NP_848749.2  cysteine/serine-rich nuclear protein 3 isoform a

    See identical proteins and their annotated locations for NP_848749.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AK082649, AL929230, BY297754, EF210820
    Consensus CDS
    CCDS16074.2
    UniProtKB/Swiss-Prot
    P59055
    Related
    ENSMUSP00000055719.4, ENSMUST00000053910.10
    Conserved Domains (1) summary
    pfam16019
    Location:73290
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    65675628..65866958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252233.1XP_030108093.1  cysteine/serine-rich nuclear protein 3 isoform X1

    Conserved Domains (1) summary
    pfam16019
    Location:73290
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  2. XM_030252234.1XP_030108094.1  cysteine/serine-rich nuclear protein 3 isoform X1

    Conserved Domains (1) summary
    pfam16019
    Location:73290
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  3. XM_030252235.1XP_030108095.1  cysteine/serine-rich nuclear protein 3 isoform X2

    Conserved Domains (1) summary
    pfam16019
    Location:61278
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  4. XM_036162720.1XP_036018613.1  cysteine/serine-rich nuclear protein 3 isoform X2

    Conserved Domains (1) summary
    pfam16019
    Location:61278
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  5. XM_030252237.1XP_030108097.1  cysteine/serine-rich nuclear protein 3 isoform X2

    Conserved Domains (1) summary
    pfam16019
    Location:61278
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
  6. XM_030252236.1XP_030108096.1  cysteine/serine-rich nuclear protein 3 isoform X2

    Conserved Domains (1) summary
    pfam16019
    Location:61278
    CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
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