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ireb2 iron responsive element binding protein 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 780221, updated on 5-Mar-2024

Summary

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Official Symbol
ireb2provided by Xenbase
Official Full Name
iron responsive element binding protein 2provided by Xenbase
Primary source
Xenbase:XB-GENE-943197
See related
Ensembl:ENSXETG00000009774
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (90917423..90964403, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (81284181..81315476, complement)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116409756 Neighboring gene transfer RNA histidin (anticodon GUG) Neighboring gene stimulated by retinoic acid gene 6 protein-like Neighboring gene uncharacterized LOC105947764 Neighboring gene cellular retinoic acid binding protein 1 Neighboring gene hypothetical protein LOC100496311

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Clone Names

  • MGC147508

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables aconitate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-responsive element binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-responsive element binding IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in citrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within intracellular iron ion homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
iron-responsive element-binding protein 2
Names
IRE-BP 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079296.1 → NP_001072764.1  iron-responsive element-binding protein 2

    See identical proteins and their annotated locations for NP_001072764.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125797
    UniProtKB/Swiss-Prot
    A0JMA0
    UniProtKB/TrEMBL
    A0A6I8RKT4
    Conserved Domains (1) summary
    cl28376
    Location:1 → 955
    AcnA; Aconitase A [Energy production and conversion]

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    90917423..90964403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012966754.3 → XP_012822208.1  iron-responsive element-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RKT4, A0A6I8S8X9
    Related
    ENSXETP00000091257.2, ENSXETT00000068513.2
    Conserved Domains (1) summary
    PTZ00092
    Location:25 → 982
    PTZ00092; aconitate hydratase-like protein; Provisional
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0JMA0.1 GenPept UniProtKB/Swiss-Prot:A0JMA0

Gene LinkOut

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