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Tmem247 transmembrane protein 247 [ Mus musculus (house mouse) ]

Gene ID: 78469, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem247provided by MGI
Official Full Name
transmembrane protein 247provided by MGI
Primary source
MGI:MGI:1925719
See related
Ensembl:ENSMUSG00000037689 AllianceGenome:MGI:1925719
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700090G07Rik
Summary
Located in endoplasmic reticulum. Orthologous to human TMEM247 (transmembrane protein 247). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 229.1) See more
Orthologs
human all
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Genomic context

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Location:
17 E4; 17 56.9 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (87224776..87229795)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (86917348..86922367)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr17:87102943-87103244 Neighboring gene aldo-keto reductase family 1, member B8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_43489 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:87131580-87131689 Neighboring gene STARR-seq mESC enhancer starr_43493 Neighboring gene STARR-seq mESC enhancer starr_43494 Neighboring gene endothelial PAS domain protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:87201221-87201489 Neighboring gene STARR-seq mESC enhancer starr_43496 Neighboring gene STARR-positive B cell enhancer ABC_E11652 Neighboring gene STARR-positive B cell enhancer ABC_E10976 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:87357353-87357462 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E2 Neighboring gene predicted gene, 57642 Neighboring gene ras homolog family member Q

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells. Hong S, et al. J Biol Chem, 2005 Mar 4. PMID 15613475
  2. Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library. Choi E, et al. BMC Genomics, 2007 Jul 28. PMID 17662146, Free PMC Article
  3. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 247
Names
transmembrane protein ENSP00000343375 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277980.1 → NP_001264909.1  transmembrane protein 247 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (2) is longer than isoform 1.
    Source sequence(s)
    AC154492, BC100486
    UniProtKB/Swiss-Prot
    Q497K7
    Conserved Domains (1) summary
    pfam15444
    Location:1 → 212
    TMEM247; Transmembrane protein 247

  2. NM_030104.1 → NP_084380.1  transmembrane protein 247 isoform 1

    See identical proteins and their annotated locations for NP_084380.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
    Source sequence(s)
    AC154492, BC100486
    Consensus CDS
    CCDS79579.1
    UniProtKB/Swiss-Prot
    Q497K7, Q8BVQ7, Q9CU05
    Related
    ENSMUSP00000039338.6, ENSMUST00000042172.7
    Conserved Domains (1) summary
    pfam15444
    Location:1 → 211
    TMEM247; Transmembrane protein 247

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    87224776..87229795
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q497K7.2 GenPept UniProtKB/Swiss-Prot:Q497K7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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