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AIRE autoimmune regulator [ Bos taurus (cattle) ]

Gene ID: 784775, updated on 3-Apr-2024

Summary

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Official Symbol
AIREprovided by VGNC
Official Full Name
autoimmune regulatorprovided by VGNC
Primary source
VGNC:VGNC:53512
See related
Ensembl:ENSBTAG00000023393
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (144287825..144298418)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene inducible T cell costimulator ligand Neighboring gene DNA methyltransferase 3 like Neighboring gene phosphofructokinase, liver type Neighboring gene cilia and flagella associated protein 410

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
autoimmune regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    144287825..144298418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024996717.2 → XP_024852485.1  autoimmune regulator isoform X2

    UniProtKB/TrEMBL
    E1BIC4
    Related
    ENSBTAP00000031798.5, ENSBTAT00000031852.5
    Conserved Domains (5) summary
    cd15539
    Location:306 → 348
    PHD1_AIRE; PHD finger 1 found in autoimmune regulator (AIRE)
    cd15540
    Location:441 → 483
    PHD2_AIRE; PHD finger 2 found in autoimmune regulator (AIRE)
    pfam03172
    Location:22 → 109
    HSR; HSR domain
    cl02536
    Location:206 → 270
    SAND; SAND domain
    cl02608
    Location:326 → 372
    BAH; or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...

  2. XM_059889442.1 → XP_059745425.1  autoimmune regulator isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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