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Micu3 mitochondrial calcium uptake family, member 3 [ Mus musculus (house mouse) ]

Gene ID: 78506, updated on 23-Jun-2021

Summary

Official Symbol
Micu3provided by MGI
Official Full Name
mitochondrial calcium uptake family, member 3provided by MGI
Primary source
MGI:MGI:1925756
See related
Ensembl:ENSMUSG00000039478
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Efha; Efha2; 2900075B16Rik
Expression
Biased expression in cerebellum adult (RPKM 8.6), frontal lobe adult (RPKM 5.7) and 10 other tissues See more
Orthologs
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Genomic context

See Micu3 in Genome Data Viewer
Location:
8; 8 A4
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (40760394..40841824)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (40307438..40388782)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (41393405..41471658)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L3 pseudogene Neighboring gene fibroblast growth factor 20 Neighboring gene microRNA 7666 Neighboring gene zinc finger, DHHC domain containing 2 Neighboring gene CCR4-NOT transcription complex, subunit 7 Neighboring gene vacuolar protein sorting 37A Neighboring gene myotubularin related protein 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in calcium import into the mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitochondrial calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
part_of uniplex complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
calcium uptake protein 3, mitochondrial
Names
EF-hand domain family, member A2
EF-hand domain-containing family member A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030110.2NP_084386.1  calcium uptake protein 3, mitochondrial

    See identical proteins and their annotated locations for NP_084386.1

    Status: VALIDATED

    Source sequence(s)
    AC102680, AC160537
    Consensus CDS
    CCDS52545.1
    UniProtKB/Swiss-Prot
    Q9CTY5
    Related
    ENSMUSP00000070241.8, ENSMUST00000068999.14
    Conserved Domains (2) summary
    pfam05763
    Location:349437
    DUF835; Protein of unknown function (DUF835)
    pfam13833
    Location:442495
    EF-hand_8; EF-hand domain pair

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    40760394..40841824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509522.4XP_006509585.1  calcium uptake protein 3, mitochondrial isoform X1

    Conserved Domains (2) summary
    PTZ00183
    Location:231346
    PTZ00183; centrin; Provisional
    cd16175
    Location:229483
    EFh_MICU3; EF-hand, calcium binding motif, found in calcium uptake protein 3, mitochondrial (MICU3) and similar proteins
  2. XM_017313013.3XP_017168502.1  calcium uptake protein 3, mitochondrial isoform X2

    Conserved Domains (1) summary
    cd16175
    Location:60327
    EFh_MICU3; EF-hand, calcium binding motif, found in calcium uptake protein 3, mitochondrial (MICU3) and similar proteins
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