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Nrip3 nuclear receptor interacting protein 3 [ Mus musculus (house mouse) ]

Gene ID: 78593, updated on 12-Mar-2024

Summary

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Official Symbol
Nrip3provided by MGI
Official Full Name
nuclear receptor interacting protein 3provided by MGI
Primary source
MGI:MGI:1925843
See related
Ensembl:ENSMUSG00000034825 AllianceGenome:MGI:1925843
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D7H11orf14; A330103B05Rik; ICRFP703B1614Q5.2
Summary
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including alimentary system; nervous system; olfactory epithelium; retina layer; and vibrissa. Orthologous to human NRIP3 (nuclear receptor interacting protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 38.6), cerebellum adult (RPKM 13.0) and 2 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 E3; 7 57.49 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (109357263..109380752, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (109758056..109781545, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene basic transcription factor 3 pseudogene Neighboring gene TMEM9 domain family, member B Neighboring gene predicted gene, 22822 Neighboring gene signal peptide, CUB domain, EGF-like 2 Neighboring gene STARR-seq mESC enhancer starr_19808 Neighboring gene STARR-seq mESC enhancer starr_19809 Neighboring gene DENN domain containing 5A Neighboring gene STARR-seq mESC enhancer starr_19810

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis. Hung CH, et al. Int J Mol Sci, 2021 Jul 27. PMID 34360789, Free PMC Article
  2. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. Amid C, et al. Cytogenet Cell Genet, 2001. PMID 11528127
  3. MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Kay JN, et al. Nature, 2012 Mar 11. PMID 22407321, Free PMC Article
  4. The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex. Schilling K, et al. Cerebellum, 2009 Dec. PMID 19554387
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Hutchins JR, et al. Science, 2010 Apr 30. PMID 20360068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
nuclear receptor-interacting protein 3
Names
ICRFP703N2430Q5.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020610.1 → NP_065635.1  nuclear receptor-interacting protein 3

    See identical proteins and their annotated locations for NP_065635.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ400878
    Consensus CDS
    CCDS21739.1
    UniProtKB/Swiss-Prot
    Q8BUN8, Q9JJR9
    UniProtKB/TrEMBL
    Q6GQT2
    Related
    ENSMUSP00000033331.7, ENSMUST00000033331.7
    Conserved Domains (1) summary
    cd05480
    Location:109 → 211
    NRIP_C; NRIP_C; putative nuclear receptor interacting protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    109357263..109380752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9JJR9.1 GenPept UniProtKB/Swiss-Prot:Q9JJR9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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