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Polr3h polymerase (RNA) III (DNA directed) polypeptide H [ Mus musculus (house mouse) ]

Gene ID: 78929, updated on 16-Oct-2021

Summary

Official Symbol
Polr3hprovided by MGI
Official Full Name
polymerase (RNA) III (DNA directed) polypeptide Hprovided by MGI
Primary source
MGI:MGI:1926179
See related
Ensembl:ENSMUSG00000022476
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RPC8; 5031409G22Rik
Expression
Ubiquitous expression in spleen adult (RPKM 15.6), cortex adult (RPKM 10.0) and 28 other tissues See more
Orthologs
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Genomic context

See Polr3h in Genome Data Viewer
Location:
15; 15 E1
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (81799231..81813824, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (81915030..81926247, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (81745460..81756643, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene transducer of ERBB2, 2 Neighboring gene PHD finger protein 5A Neighboring gene aconitase 2, mitochondrial Neighboring gene cold shock domain containing C2, RNA binding Neighboring gene phosphomannomutase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-directed 5'-3' RNA polymerase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to virus IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleobase-containing compound metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
involved_in transcription initiation from RNA polymerase III promoter IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of RNA polymerase III complex ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerase III subunit RPC8
Names
DNA-directed RNA polymerase III subunit H
RNA polymerase III subunit C7
NP_084505.2
XP_006521608.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_030229.4NP_084505.2  DNA-directed RNA polymerase III subunit RPC8

    See identical proteins and their annotated locations for NP_084505.2

    Status: PROVISIONAL

    Source sequence(s)
    AC102103
    Consensus CDS
    CCDS27676.1
    UniProtKB/Swiss-Prot
    Q9D2C6
    Related
    ENSMUSP00000023113.6, ENSMUST00000023113.7
    Conserved Domains (2) summary
    cd04330
    Location:281
    RNAP_III_Rpc25_N; Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, an N-terminal RNP ...
    pfam08292
    Location:83201
    RNA_pol_Rbc25; RNA polymerase III subunit Rpc25

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    81799231..81813824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521545.4XP_006521608.1  DNA-directed RNA polymerase III subunit RPC8 isoform X1

    Conserved Domains (2) summary
    cd04330
    Location:281
    RNAP_III_Rpc25_N; Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, an N-terminal RNP ...
    cl09927
    Location:79119
    S1_like; Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains ...

RNA

  1. XR_001781579.3 RNA Sequence

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