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Zfp354c zinc finger protein 354C [ Rattus norvegicus (Norway rat) ]

Gene ID: 78972, updated on 30-Sep-2021

Summary

Official Symbol
Zfp354cprovided by RGD
Official Full Name
zinc finger protein 354Cprovided by RGD
Primary source
RGD:69405
See related
EnsemblRapid:ENSRNOG00000029205
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Aj18; Zfn354c; Znf354c
Summary
zinc finger transcription factor; modulates Runx2 activity and osteogenic differentiation [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 68.7), Uterus (RPKM 37.6) and 9 other tissues See more
Orthologs
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Genomic context

See Zfp354c in Genome Data Viewer
Location:
10q22
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35129720..35145717, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (36311343..36322356, complement)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095319 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 2 Neighboring gene zinc finger protein 879 Neighboring gene glutamate metabotropic receptor 6

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger protein 354C
Names
zinc finger transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023988.1NP_076478.1  zinc finger protein 354C

    See identical proteins and their annotated locations for NP_076478.1

    Status: PROVISIONAL

    Source sequence(s)
    AF321874
    UniProtKB/Swiss-Prot
    Q9EPU7
    Conserved Domains (5) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:208557
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:248268
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:456481
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    35129720..35145717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086905.1XP_038942833.1  zinc finger protein 354C isoform X1

    Related
    ENSRNOP00000000248.1, ENSRNOT00000000248.3
    Conserved Domains (3) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:208557
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:248268
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_039086907.1XP_038942835.1  zinc finger protein 354C isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:208557
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:248268
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_039086908.1XP_038942836.1  zinc finger protein 354C isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:135484
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:175195
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_039086906.1XP_038942834.1  zinc finger protein 354C isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:208557
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:248268
    ZF_C2H2; C2H2 Zn finger [structural motif]
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