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Aco2 aconitase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 79250, updated on 6-May-2021

Summary

Official Symbol
Aco2provided by RGD
Official Full Name
aconitase 2provided by RGD
Primary source
RGD:621360
See related
Ensembl:ENSRNOG00000024128
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Heart (RPKM 5609.7), Muscle (RPKM 4060.0) and 7 other tissues See more
Orthologs
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Genomic context

See Aco2 in Genome Data Viewer
Location:
7q34
Exon count:
18
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (113385677..113428794)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (123102493..123145608)

Chromosome 7 - NC_051342.1Genomic Context describing neighboring genes Neighboring gene transducer of ERBB2, 2 Neighboring gene PHD finger protein 5A Neighboring gene RNA polymerase III subunit H Neighboring gene uncharacterized LOC102549144 Neighboring gene small nucleolar RNA SNORA44

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 3 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables aconitate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables aconitate hydratase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables aconitate hydratase activity ISO
Inferred from Sequence Orthology
more info
 
enables citrate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables iron ion binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in citrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within citrate metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in isocitrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in liver development IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to isolation stress IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tricarboxylic acid cycle IDA
Inferred from Direct Assay
more info
PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within tricarboxylic acid cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
aconitate hydratase, mitochondrial
Names
aconitase 2, mitochondrial
citrate hydro-lyase
mitochondrial aconitase (nuclear aco2 gene)
NP_077374.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024398.2NP_077374.2  aconitate hydratase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_077374.2

    Status: PROVISIONAL

    Source sequence(s)
    BC061999
    UniProtKB/Swiss-Prot
    Q9ER34
    Related
    ENSRNOP00000029144.3, ENSRNOT00000038612.5
    Conserved Domains (1) summary
    TIGR01340
    Location:45775
    aconitase_mito; aconitate hydratase, mitochondrial

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051342.1 Reference mRatBN7.2 Primary Assembly

    Range
    113385677..113428794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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