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LOC8053058 signal transducer and activator of transcription 5A [ Ixodes scapularis (black-legged tick) ]

Gene ID: 8053058, updated on 11-Apr-2024

Summary

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Gene symbol
LOC8053058
Gene description
signal transducer and activator of transcription 5A
See related
VectorBase:ISCP_004695; EnsemblRapid:LOC8053058
Gene type
protein coding
RefSeq status
MODEL
Organism
Ixodes scapularis
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes
Also known as
STAT
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Genomic context

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See LOC8053058 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
103 current ASM1692078v2 (GCF_016920785.2) Unplaced Scaffold NW_024609835.1 (5119510..5186071)
102 previous assembly Ixodes_scapularus_ComboLowHiFi (GCF_016920785.1) Unplaced Scaffold NW_024388156.1 (3819138..3885699, complement)

NW_024609835.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC8053060 Neighboring gene sulfotransferase ssu-1 Neighboring gene uncharacterized LOC120842440 Neighboring gene probable 39S ribosomal protein L45, mitochondrial

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ixodes scapularis JAK-STAT pathway regulates tick antimicrobial peptides, thereby controlling the agent of human granulocytic anaplasmosis. Liu L, et al. J Infect Dis, 2012 Oct. PMID 22859824, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A; signal transducer and activator of transcription 5B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ixodes scapularis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1692078v2

Genomic

  1. NW_024609835.1 Reference ASM1692078v2

    Range
    5119510..5186071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029968134.3 → XP_029823994.1  signal transducer and activator of transcription 5B isoform X1

    UniProtKB/TrEMBL
    E9NSU3
    Related
    XP_029823994.1, XM_029968134.3
    Conserved Domains (4) summary
    cd09919
    Location:584 → 699
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    cd16855
    Location:136 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 490
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain

  2. XM_029968135.4 → XP_029823995.1  signal transducer and activator of transcription 5A isoform X2

    UniProtKB/TrEMBL
    E9NSU3
    Related
    XP_029823995.1, XM_029968135.4
    Conserved Domains (4) summary
    cd09919
    Location:570 → 685
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    cd16855
    Location:136 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 490
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain

  3. XM_029968136.4 → XP_029823996.1  signal transducer and activator of transcription 5A isoform X3

    UniProtKB/TrEMBL
    A0A4D5RI83, E9NSU3
    Related
    XP_029823996.1, XM_029968136.4
    Conserved Domains (4) summary
    cd09919
    Location:584 → 699
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    cd16855
    Location:136 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 490
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    pfam02865
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain

  4. XM_040502108.2 → XP_040358042.1  signal transducer and activator of transcription 5A isoform X4

    UniProtKB/TrEMBL
    A0A4D5RKP0, E9NSU3
    Related
    XP_040358042.1, XM_040502108.2
    Conserved Domains (4) summary
    cd09919
    Location:570 → 685
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    cd16855
    Location:136 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 490
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cl03749
    Location:2 → 122
    STAT_int; STAT protein, protein interaction domain

  5. XM_040213551.3 → XP_040069485.1  signal transducer and activator of transcription 5A isoform X5

    UniProtKB/TrEMBL
    B7PKW7
    Related
    XP_040069485.1, XM_040213551.3
    Conserved Domains (4) summary
    cd09919
    Location:570 → 685
    SH2_STAT_family; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) family
    cd16855
    Location:136 → 330
    STAT5_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cd16849
    Location:332 → 490
    STAT5_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 5 (STAT5)
    cl03749
    Location:2 → 122
    STAT_int; STAT protein, protein interaction domain
Nucleotide Protein
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