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CKS1 cyclin-dependent kinase-subunit 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817340, updated on 15-Oct-2023

Summary

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Gene symbol
CKS1
Gene description
cyclin-dependent kinase-subunit 1
Primary source
Araport:AT2G27960
Locus tag
AT2G27960
See related
TAIR:AT2G27960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CATALYTIC SUBUNIT OF CYCLIN-DEPENDENT KINASE; CKS1AT; cyclin-dependent kinase-subunit 1; P10CKS1AT; T1E2.12; T1E2_12
Summary
catalytic subunit of cyclin dependent kinase 1. physically interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle
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Genomic context

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See CKS1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (11910569..11911802, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene Ring/U-Box superfamily protein Neighboring gene Acyl-CoA N-acyltransferase with RING/FYVE/PHD-type zinc finger domain-containing protein Neighboring gene CDK-subunit 2 Neighboring gene BEL1-like homeodomain 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CKS1At overexpression in Arabidopsis thaliana inhibits growth by reducing meristem size and inhibiting cell-cycle progression. De Veylder L, et al. Plant J, 2001 Mar. PMID 11319029
  2. Expression of CKS1At in Arabidopsis thaliana indicates a role for the protein in both the mitotic and the endoreduplication cycle. Jacqmard A, et al. Planta, 1999 Feb. PMID 10093894
  3. The Arabidopsis Cks1At protein binds the cyclin-dependent kinases Cdc2aAt and Cdc2bAt. De Veylder L, et al. FEBS Lett, 1997 Aug 4. PMID 9276444
  4. Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis. Boudolf V, et al. J Exp Bot, 2001 Jun. PMID 11432958
  5. Arabidopsis D-type cyclin CYCD4;1 is a novel cyclin partner of B2-type cyclin-dependent kinase. Kono A, et al. Plant Physiol, 2003 Jul. PMID 12857813, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_128355.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA endoreduplication IDA
Inferred from Direct Assay
more info
 PubMed 
NOT involved_in DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic cell cycle IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in peroxisome HDA PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase-subunit 1
NP_180363.1
  • cyclin-dependent kinase-subunit 1 (CKS1); CONTAINS InterPro DOMAIN/s: Cyclin-dependent kinase, regulatory subunit (InterPro:IPR000789); BEST Arabidopsis thaliana protein match is: CDK-subunit 2 (TAIR:AT2G27970.1); Has 657 Blast hits to 657 proteins in 207 species: Archae - 0; Bacteria - 0; Metazoa - 305; Fungi - 139; Plants - 105; Viruses - 0; Other Eukaryotes - 108 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11910569..11911802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128355.3 → NP_180363.1  cyclin-dependent kinase-subunit 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180363.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23249
    UniProtKB/TrEMBL
    A0A178VPG9, A0A5S9X202
    Conserved Domains (1) summary
    PLN00010
    Location:1 → 71
    PLN00010; cyclin-dependent kinases regulatory subunit; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O23249.1

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