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ABCC7 multidrug resistance-associated protein 7 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820498, updated on 7-Sep-2023

Summary

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Gene symbol
ABCC7
Gene description
multidrug resistance-associated protein 7
Primary source
Araport:AT3G13100
Locus tag
AT3G13100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATMRP7; ATP-binding cassette C7; multidrug resistance-associated protein 7
Summary
member of MRP subfamily
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (4208729..4214530, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene multidrug resistance-associated protein 8 Neighboring gene miscRNA Neighboring gene serine acetyltransferase 2;2 Neighboring gene Ribosomal protein S10p/S20e family protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ectopic expression of Arabidopsis ABC transporter MRP7 modifies cadmium root-to-shoot transport and accumulation. Wojas S, et al. Environ Pollut, 2009 Oct. PMID 19467746
  2. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Bartsch M, et al. Plant Cell, 2006 Apr. PMID 16531493, Free PMC Article
  3. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
  4. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Overexpression of MRP7 modifies cadmium root-to-shoot transport and accumulation.
    Title: Ectopic expression of Arabidopsis ABC transporter MRP7 modifies cadmium root-to-shoot transport and accumulation.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_001338032.1
NM_112149.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ABC-type xenobiotic transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to other organism IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plant-type vacuole HDA PubMed 

General protein information

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Preferred Names
multidrug resistance-associated protein 7
NP_187917.3
  • multidrug resistance-associated protein 7 (MRP7); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to other organism; LOCATED IN: plasma membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 8 (TAIR:AT3G13090.1); Has 650648 Blast hits to 350565 proteins in 4050 species: Archae - 11697; Bacteria - 531445; Metazoa - 11792; Fungi - 6984; Plants - 5983; Viruses - 13; Other Eukaryotes - 82734 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4208729..4214530 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112149.4 → NP_187917.3  multidrug resistance-associated protein 7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187917.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LGU0, Q9LK62
    UniProtKB/TrEMBL
    A0A178VBI7
    Conserved Domains (4) summary
    cd03244
    Location:1239 → 1459
    ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
    cd03250
    Location:624 → 824
    ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
    PLN03232
    Location:34 → 1474
    PLN03232; ABC transporter C family member; Provisional
    cl00549
    Location:925 → 1199
    ABC_membrane; ABC transporter transmembrane region

  2. NM_001338032.1 → NP_001325667.1  multidrug resistance-associated protein 7 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LLY2, A0A654F6N9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LK62.1

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