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AT3G59940 Galactose oxidase/kelch repeat superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825164, updated on 7-Sep-2023

Summary

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Gene symbol
AT3G59940
Gene description
Galactose oxidase/kelch repeat superfamily protein
Primary source
Araport:AT3G59940
Locus tag
AT3G59940
See related
TAIR:AT3G59940
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
Kelch repeat F-box 50; KFB50; KISS ME DEADLY 4; KMD4
Summary
Encodes a member of a family of F-box proteins, called the KISS ME DEADLY (KMD) family, that targets type-B ARR proteins for degradation and is involved in the negative regulation of the cytokinin response. Also named as KFB50, a member of a group of Kelch repeat F-box proteins that negatively regulate phenylpropanoid biosynthesis by targeting the phenypropanoid biosynthesis enzyme phenylalanine ammonia-lyase.
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Genomic context

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See AT3G59940 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_003074.8 (22142856..22144439)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene defensin-like protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peptidase family C54 protein Neighboring gene ncRNA Neighboring gene histone-lysine N-methyltransferase ASHH4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase. Zhang X, et al. Plant Cell, 2013 Dec. PMID 24363316, Free PMC Article
  2. SCF(KMD) controls cytokinin signaling by regulating the degradation of type-B response regulators. Kim HJ, et al. Proc Natl Acad Sci U S A, 2013 Jun 11. PMID 23720308, Free PMC Article
  3. ABC transporter PEN3/PDR8/ABCG36 interacts with calmodulin that, like PEN3, is required for Arabidopsis nonhost resistance. Campe R, et al. New Phytol, 2016 Jan. PMID 26315018
  4. Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Risseeuw EP, et al. Plant J, 2003 Jun. PMID 12795696
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115857.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of cytokinin-activated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of phenylpropanoid metabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Galactose oxidase/kelch repeat superfamily protein
NP_191553.1
  • Galactose oxidase/kelch repeat superfamily protein; CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 1 (InterPro:IPR006652), Kelch related (InterPro:IPR013089), Kelch-type beta propeller (InterPro:IPR015915); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT2G44130.1); Has 2977 Blast hits to 2510 proteins in 188 species: Archae - 4; Bacteria - 251; Metazoa - 1720; Fungi - 24; Plants - 858; Viruses - 0; Other Eukaryotes - 120 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    22142856..22144439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115857.2 → NP_191553.1  Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191553.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L991, Q9M1Y1
    UniProtKB/TrEMBL
    A0A178VAS9, A0A5S9XN35, A0A654FJD4
    Conserved Domains (4) summary
    smart00256
    Location:19 → 59
    FBOX; A Receptor for Ubiquitination Targets
    PHA03098
    Location:121 → 296
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:196 → 242
    Kelch; KELCH repeat [structural motif]
    pfam01344
    Location:195 → 242
    Kelch_1; Kelch motif
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M1Y1.1

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