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DHS2 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829489, updated on 7-Sep-2023

Summary

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Gene symbol
DHS2
Gene description
3-deoxy-d-arabino-heptulosonate 7-phosphate synthase
Primary source
Araport:AT4G33510
Locus tag
AT4G33510
See related
TAIR:AT4G33510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE; 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE 2; AtDAHP2; DAHP2; F17M5.270; F17M5_270
Summary
Enzyme catalyzing the first committed step in aromatic amino acid biosynthesis
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Genomic context

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See DHS2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (16116371..16118825)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene BTB/POZ domain protein TNFAIP protein Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene Protein phosphatase 2C family protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene P-type ATP-ase 1 Neighboring gene K+ uptake permease 5 Neighboring gene metallo-beta-lactamase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. Keith B, et al. Proc Natl Acad Sci U S A, 1991 Oct 1. PMID 1681544, Free PMC Article
  2. Arabidopsis TRANSCURVATA1 encodes NUP58, a component of the nucleopore central channel. Ferrández-Ayela A, et al. PLoS One, 2013. PMID 23840761, Free PMC Article
  3. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
  4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
  5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001342217.1
NM_119505.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-deoxy-7-phosphoheptulonate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables 3-deoxy-7-phosphoheptulonate synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within aromatic amino acid family biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in chorismate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chorismate biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast TAS
Traceable Author Statement
more info
 PubMed 
located_in chloroplast thylakoid HDA PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
3-deoxy-d-arabino-heptulosonate 7-phosphate synthase
NP_001320125.1
  • 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DHS2); FUNCTIONS IN: protein binding, 3-deoxy-7-phosphoheptulonate synthase activity; INVOLVED IN: chorismate biosynthetic process, aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase, class II (InterPro:IPR002480); BEST Arabidopsis thaliana protein match is: Class-II DAHP synthetase family protein (TAIR:AT1G22410.1); Has 3601 Blast hits to 3584 proteins in 682 species: Archae - 0; Bacteria - 1231; Metazoa - 0; Fungi - 107; Plants - 172; Viruses - 0; Other Eukaryotes - 2091 (source: NCBI BLink).
NP_195077.1
  • 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DHS2); FUNCTIONS IN: protein binding, 3-deoxy-7-phosphoheptulonate synthase activity; INVOLVED IN: chorismate biosynthetic process, aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase, class II (InterPro:IPR002480); BEST Arabidopsis thaliana protein match is: Class-II DAHP synthetase family protein (TAIR:AT1G22410.1); Has 3818 Blast hits to 3801 proteins in 685 species: Archae - 0; Bacteria - 1238; Metazoa - 0; Fungi - 112; Plants - 173; Viruses - 0; Other Eukaryotes - 2295 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    16116371..16118825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119505.3 → NP_195077.1  3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195077.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q00218, Q9SZC8
    UniProtKB/TrEMBL
    A0A178US70, A0A5S9XYA1, A0A7G2F9I3, Q8LAR5
    Conserved Domains (1) summary
    PLN02291
    Location:34 → 506
    PLN02291; phospho-2-dehydro-3-deoxyheptonate aldolase

  2. NM_001342217.1 → NP_001320125.1  3-deoxy-d-arabino-heptulosonate 7-phosphate synthase [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JIZ3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q00218.2

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