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TMUB1 transmembrane and ubiquitin like domain containing 1 [ Homo sapiens (human) ]

Gene ID: 83590, updated on 23-Nov-2021

Summary

Official Symbol
TMUB1provided by HGNC
Official Full Name
transmembrane and ubiquitin like domain containing 1provided by HGNC
Primary source
HGNC:HGNC:21709
See related
Ensembl:ENSG00000164897 MIM:614792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DULP; HOPS; SB144; C7orf21
Expression
Ubiquitous expression in colon (RPKM 10.6), kidney (RPKM 10.4) and 25 other tissues See more
Orthologs
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Genomic context

See TMUB1 in Genome Data Viewer
Location:
7q36.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (151081085..151083493, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (150778172..150780580, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene solute carrier family 4 member 2 Neighboring gene Sharpr-MPRA regulatory region 12172 Neighboring gene Fas activated serine/threonine kinase Neighboring gene uncharacterized LOC107986862 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Neighboring gene gastrulation brain homeobox 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC5442

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ubiquitin-dependent ERAD pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule organizing center IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 
located_in recycling endosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane and ubiquitin-like domain-containing protein 1
Names
dendritic cell-derived ubiquitin-like protein
hepatocyte odd protein shuttling protein
ubiquitin-like protein DULP
ubiquitin-like protein SB144

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001136044.2NP_001129516.1  transmembrane and ubiquitin-like domain-containing protein 1

    See identical proteins and their annotated locations for NP_001129516.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate 5' UTR exon, as compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC000936
    Consensus CDS
    CCDS5920.1
    UniProtKB/Swiss-Prot
    Q9BVT8
    UniProtKB/TrEMBL
    A0A090N8Q3
    Related
    ENSP00000297533.4, ENST00000297533.9
    Conserved Domains (1) summary
    cd17131
    Location:102172
    Ubl_TMUB1; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1)
  2. NM_031434.4NP_113622.1  transmembrane and ubiquitin-like domain-containing protein 1

    See identical proteins and their annotated locations for NP_113622.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC000936, BC033182, DA355717
    Consensus CDS
    CCDS5920.1
    UniProtKB/Swiss-Prot
    Q9BVT8
    UniProtKB/TrEMBL
    A0A090N8Q3
    Related
    ENSP00000376565.3, ENST00000392818.7
    Conserved Domains (1) summary
    cd17131
    Location:102172
    Ubl_TMUB1; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    151081085..151083493 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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