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HCA2 Dof-type zinc finger DNA-binding family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836414, updated on 7-Sep-2023

Summary

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Gene symbol
HCA2
Gene description
Dof-type zinc finger DNA-binding family protein
Primary source
Araport:AT5G62940
Locus tag
AT5G62940
See related
TAIR:AT5G62940
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DNA BINDING WITH ONE FINGER 5.6; DOF5.6; HIGH CAMBIAL ACTIVITY2; MQB2.26; MQB2_26
Summary
HCA2 induces the formation of interfascicular cambium and regulates vascular tissue development in the aerial parts of the plant. Evidence from both gain of function and dominant negative alleles.
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Genomic context

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See HCA2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (25256852..25258704, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene response regulator 6 Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene RNA polymerase II, Rpb4, core protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dof5.6/HCA2, a Dof transcription factor gene, regulates interfascicular cambium formation and vascular tissue development in Arabidopsis. Guo Y, et al. Plant Cell, 2009 Nov. PMID 19915089, Free PMC Article
  2. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Miyashima S, et al. Nature, 2019 Jan. PMID 30626969
  3. The Dof family of plant transcription factors. Yanagisawa S. Trends Plant Sci, 2002 Dec. PMID 12475498
  4. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article
  5. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This report demonstrates that a transcription factor gene, HCA2, is involved in regulation of interfascicular cambium formation and vascular tissue development in Arabidopsis.[HCA2]
    Title: Dof5.6/HCA2, a Dof transcription factor gene, regulates interfascicular cambium formation and vascular tissue development in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_125688.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within phloem or xylem histogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within procambium histogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within root radial pattern formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Dof-type zinc finger DNA-binding family protein
NP_201099.1
  • HIGH CAMBIAL ACTIVITY2 (HCA2); CONTAINS InterPro DOMAIN/s: Zinc finger, Dof-type (InterPro:IPR003851); BEST Arabidopsis thaliana protein match is: TARGET OF MONOPTEROS 6 (TAIR:AT5G60200.1); Has 1915 Blast hits to 1778 proteins in 135 species: Archae - 0; Bacteria - 49; Metazoa - 135; Fungi - 61; Plants - 1116; Viruses - 0; Other Eukaryotes - 554 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    25256852..25258704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125688.3 → NP_201099.1  Dof-type zinc finger DNA-binding family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201099.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WPR9, Q5HZ57, Q9FM03
    UniProtKB/TrEMBL
    A0A178UF22, A0A5S9YIQ4
    Conserved Domains (1) summary
    pfam02701
    Location:72 → 123
    zf-Dof; Dof domain, zinc finger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FM03.2

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