AT1G06790 RNA polymerase Rpb7 N-terminal domain-containing protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Gene symbol: AT1G06790
Gene description: RNA polymerase Rpb7 N-terminal domain-containing protein
Primary source: Araport:AT1G06790
Locus tag: AT1G06790
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F4H5.12; F4H5_12
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Genomic context

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Location:: chromosome: 1

Exon count:: 8

Sequence:: Chromosome: 1; NC_003070.9 (2087182..2089786)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

nrpc7-1, a partial loss-of-function allele of the gene encoding the Arabidopsis orthologue of yeast Rpc25, a Pol III subunit. A null mutation in NRPC7 is lethal, while a mutation in an intron-exon splice site junction gives rise to intronic retention in some NRPC7 transcripts, resulting in viable mutant plants. NRPC7 protein localizes to the nucleus. [NRPC7]
Title: A partial loss-of-function mutation in an Arabidopsis RNA polymerase III subunit leads to pleiotropic defects.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_100556.5

Supported by ESTs:

NM_202047.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within RNA splicing	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: RNA polymerase Rpb7 N-terminal domain-containing protein

NP_172164.1

RNA polymerase Rpb7 N-terminal domain-containing protein; FUNCTIONS IN: DNA-directed RNA polymerase activity; INVOLVED IN: transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase Rpb7, N-terminal (InterPro:IPR005576), RNA polymerase III, subunit Rpc25 (InterPro:IPR013238); Has 892 Blast hits to 892 proteins in 299 species: Archae - 169; Bacteria - 0; Metazoa - 273; Fungi - 266; Plants - 84; Viruses - 0; Other Eukaryotes - 100 (source: NCBI BLink).

NP_973776.1

RNA polymerase Rpb7 N-terminal domain-containing protein; FUNCTIONS IN: DNA-directed RNA polymerase activity; INVOLVED IN: transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase Rpb7, N-terminal (InterPro:IPR005576), RNA polymerase III, subunit Rpc25 (InterPro:IPR013238); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

2087182..2089786

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_100556.5 → NP_172164.1 RNA polymerase Rpb7 N-terminal domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172164.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178WGX6, Q9M9Y6

Conserved Domains (2) summary

COG1095
Location:1 → 194

RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]

cd04330
Location:2 → 81

RNAP_III_Rpc25_N; Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, an N-terminal RNP ...
NM_202047.1 → NP_973776.1 RNA polymerase Rpb7 N-terminal domain-containing protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973776.1

Status: REVIEWED

UniProtKB/TrEMBL

F4HNT3

Conserved Domains (2) summary

COG1095
Location:1 → 163

RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]

cd04330
Location:2 → 81

RNAP_III_Rpc25_N; Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, an N-terminal RNP ...