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DET3 vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837840, updated on 7-Sep-2023

Summary

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Gene symbol
DET3
Gene description
vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3)
Primary source
Araport:AT1G12840
Locus tag
AT1G12840
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA VACUOLAR ATP SYNTHASE SUBUNIT C; ATVHA-C; DE-ETIOLATED 3; F13K23.9; F13K23_9; VACUOLAR ATP SYNTHASE SUBUNIT C
Summary
Encodes subunit C of the vacuolar H(+)-ATPase (V-ATPase). Bound and phosphorylated by AtWNK8.
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Genomic context

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Location:
chromosome: 1
Exon count:
11
Sequence:
Chromosome: 1; NC_003070.9 (4374205..4378514)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene proline-rich family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene auxin signaling F-box 3 Neighboring gene nucleolin Neighboring gene uncharacterized protein Neighboring gene Phosphoglycerate mutase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis det3 mutant reveals a central role for the vacuolar H(+)-ATPase in plant growth and development. Schumacher K, et al. Genes Dev, 1999 Dec 15. PMID 10617574, Free PMC Article
  2. A WNK kinase binds and phosphorylates V-ATPase subunit C. Hong-Hermesdorf A, et al. FEBS Lett, 2006 Feb 6. PMID 16427632
  3. Comparison of lignin deposition in three ectopic lignification mutants. Rogers LA, et al. New Phytol, 2005 Oct. PMID 16159327
  4. SOS2 promotes salt tolerance in part by interacting with the vacuolar H+-ATPase and upregulating its transport activity. Batelli G, et al. Mol Cell Biol, 2007 Nov. PMID 17875927, Free PMC Article
  5. Arabidopsis TRANSCURVATA1 encodes NUP58, a component of the nucleopore central channel. Ferrández-Ayela A, et al. PLoS One, 2013. PMID 23840761, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_101154.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
contributes_to proton-transporting ATPase activity, rotational mechanism IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within lignin biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of carbohydrate biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in chloroplast HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vacuolar membrane HDA PubMed 
part_of vacuolar proton-transporting V-type ATPase, V1 domain IDA
Inferred from Direct Assay
more info
 PubMed 
located_in vacuole HDA PubMed 

General protein information

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Preferred Names
vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3)
NP_563916.1
  • DE-ETIOLATED 3 (DET3); FUNCTIONS IN: proton-transporting ATPase activity, rotational mechanism; INVOLVED IN: lignin biosynthetic process, regulation of carbohydrate biosynthetic process, unidimensional cell growth; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, V1 complex, subunit C (InterPro:IPR004907); Has 563 Blast hits to 541 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 263; Fungi - 140; Plants - 72; Viruses - 0; Other Eukaryotes - 88 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    4374205..4378514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101154.4 → NP_563916.1  vacuolar ATP synthase subunit C (VATC) / V-ATPase C subunit / vacuolar proton pump C subunit (DET3) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_563916.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SDS7
    UniProtKB/TrEMBL
    A0A178WM16, A0A384KX64, C0SUV0
    Conserved Domains (2) summary
    cd14785
    Location:57 → 77
    V-ATPase_C; 3-helical coiled coil [structural motif]
    pfam03223
    Location:6 → 368
    V-ATPase_C; V-ATPase subunit C
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SDS7.1

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