U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rps2 ribosomal protein S2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 83789, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Rps2provided by RGD
Official Full Name
ribosomal protein S2provided by RGD
Primary source
RGD:619887
See related
Ensembl:ENSRNOG00000014179 AllianceGenome:RGD:619887
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rps2r1
Summary
A structural constituent of ribosome. Involved in formation of translation preinitiation complex; response to ethanol; and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Orthologous to human RPS2 (ribosomal protein S2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Spleen (RPKM 5380.6), Thymus (RPKM 4322.0) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
10q12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (14251841..14253697)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (13747316..13749165)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (14088171..14090020)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene transducin (beta)-like 3 Neighboring gene ring finger protein 151 Neighboring gene small nucleolar RNA ACA64 Neighboring gene small nucleolar RNA, H/ACA box 64 Neighboring gene NADH:ubiquinone oxidoreductase subunit B10 Neighboring gene ribosomal protein L3-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Localization of rat liver ribosomal protein S2 and its involvement in initiation factor eIF-2 binding to the 40 S ribosomal subunit. Noll F, et al. FEBS Lett, 1978 Mar 1. PMID 344063
  2. Identification of an unconventional nuclear localization signal in human ribosomal protein S2. Antoine M, et al. Biochem Biophys Res Commun, 2005 Sep 16. PMID 16061210
  3. Primary structure of rat ribosomal protein S2. A ribosomal protein with arginine-glycine tandem repeats and RGGF motifs that are associated with nucleolar localization and binding to ribonucleic acids. Suzuki K, et al. J Biol Chem, 1991 Oct 25. PMID 1939063
  4. Physical mapping and structural analysis of new gene families RT1.S and Rps2r in the grc region of the rat major histocompatibility complex. Salgar SK, et al. Immunogenetics, 1997. PMID 9089092
  5. PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex. Choi S, et al. Biochim Biophys Acta, 2008 Sep. PMID 18573314

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables fibroblast growth factor binding ISO
Inferred from Sequence Orthology
more info
  
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
  
enables protein-containing complex binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to interleukin-4 ISO
Inferred from Sequence Orthology
more info
  
involved_in formation of translation preinitiation complex IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to ethanol IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in ribosomal small subunit assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
NOT located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
small ribosomal subunit protein uS5
Names
40S ribosomal protein S2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031838.3 → NP_114026.3  small ribosomal subunit protein uS5

    See identical proteins and their annotated locations for NP_114026.3

    Status: PROVISIONAL

    Source sequence(s)
    AI713815, CB324420, CD372915
    UniProtKB/Swiss-Prot
    P27952, Q4G062
    UniProtKB/TrEMBL
    E9PU05, O55215
    Related
    ENSRNOP00000019508.3, ENSRNOT00000019508.7
    Conserved Domains (1) summary
    PTZ00070
    Location:54 → 273
    PTZ00070; 40S ribosomal protein S2; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    14251841..14253697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269975.1 → XP_063126045.1  small ribosomal subunit protein uS5 isoform X1

    UniProtKB/Swiss-Prot
    P27952, Q4G062
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P27952.1 GenPept UniProtKB/Swiss-Prot:P27952

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous