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Scd2 stearoyl-Coenzyme A desaturase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 83792, updated on 30-Sep-2021

Summary

Official Symbol
Scd2provided by RGD
Official Full Name
stearoyl-Coenzyme A desaturase 2provided by RGD
Primary source
RGD:621177
See related
EnsemblRapid:ENSRNOG00000046005
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Scd
Summary
enzyme involved in the regulation of oleic acid synthesis in the peripheral nervous system [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 3323.4), Adrenal (RPKM 2026.4) and 8 other tissues See more
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Genomic context

See Scd2 in Genome Data Viewer
Location:
1q54
Exon count:
6
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (243169171..243182231)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (264059374..264072433)

Chromosome 1 - NC_051336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100040 Neighboring gene uncharacterized LOC108349475 Neighboring gene stearoyl-coenzyme A desaturase 4 Neighboring gene stearoyl-CoA desaturase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables palmitoyl-CoA 9-desaturase activity IEA
Inferred from Electronic Annotation
more info
 
enables palmitoyl-CoA 9-desaturase activity ISO
Inferred from Sequence Orthology
more info
 
enables stearoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables stearoyl-CoA 9-desaturase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables stearoyl-CoA 9-desaturase activity IEA
Inferred from Electronic Annotation
more info
 
enables stearoyl-CoA 9-desaturase activity ISO
Inferred from Sequence Orthology
more info
 
enables stearoyl-CoA 9-desaturase activity TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
stearoyl-CoA desaturase 2
Names
acyl-CoA desaturase 2
delta(9)-desaturase 2
fatty acid desaturase 2
stearoyl-CoA desaturase (delta-9-desaturase)
NP_114029.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031841.2NP_114029.1  stearoyl-CoA desaturase 2

    See identical proteins and their annotated locations for NP_114029.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000054
    UniProtKB/Swiss-Prot
    Q6P7B9
    UniProtKB/TrEMBL
    M0RDU8
    Related
    ENSRNOP00000067809.1, ENSRNOT00000075397.2
    Conserved Domains (2) summary
    cd03505
    Location:99336
    Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...
    pfam00487
    Location:101305
    FA_desaturase; Fatty acid desaturase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051336.1 Reference mRatBN7.2 Primary Assembly

    Range
    243169171..243182231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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