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Tbx19 T-box 19 [ Mus musculus (house mouse) ]

Gene ID: 83993, updated on 22-Aug-2021

Summary

Official Symbol
Tbx19provided by MGI
Official Full Name
T-box 19provided by MGI
Primary source
MGI:MGI:1891158
See related
Ensembl:ENSMUSG00000026572
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tp; Tpit; AU019250; D1Ertd754; D1Ertd754e
Summary
This gene encodes a member of a family of transcription factors containing a characteristic T-box DNA-binding domain. The encoded protein promotes expression of the pro-opiomelanocortin (POMC) gene, which is important for the differentiation of cells in the pituitary gland. [provided by RefSeq, Mar 2013]
Expression
Biased expression in testis adult (RPKM 6.3) and thymus adult (RPKM 2.4) See more
Orthologs
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Genomic context

See Tbx19 in Genome Data Viewer
Location:
1 H2.2; 1 72.47 cM
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (164965403..164988342, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (165137834..165160773, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (167067984..167090904, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51669 Neighboring gene RIKEN cDNA 4930568G15 gene Neighboring gene SFT2 domain containing 2 Neighboring gene TIP41, TOR signalling pathway regulator-like (S. cerevisiae) Neighboring gene G protein-coupled receptor 161

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
T-box transcription factor TBX19
Names
T-box factor, pituitary
T-box protein 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032005.4NP_114394.1  T-box transcription factor TBX19

    See identical proteins and their annotated locations for NP_114394.1

    Status: REVIEWED

    Source sequence(s)
    AK038666, AU019700
    Consensus CDS
    CCDS15439.1
    UniProtKB/Swiss-Prot
    Q99ME7
    Related
    ENSMUSP00000027859.6, ENSMUST00000027859.12
    Conserved Domains (1) summary
    smart00425
    Location:39221
    TBOX; Domain first found in the mice T locus (Brachyury) protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    164965403..164988342 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497043.3XP_006497106.1  T-box transcription factor TBX19 isoform X1

    Related
    ENSMUSP00000123909.2, ENSMUST00000161144.2
    Conserved Domains (1) summary
    pfam00907
    Location:1149
    T-box
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