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DPMS2 dolichol phosphate-mannose biosynthesis regulatory protein-like protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843775, updated on 15-Oct-2023

Summary

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Gene symbol
DPMS2
Gene description
dolichol phosphate-mannose biosynthesis regulatory protein-like protein
Primary source
Araport:AT1G74340
Locus tag
AT1G74340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
dolichol phosphate mannose synthase 2; F1M20.2; F1M20_2
Summary
Encodes a subunit of the dolichol phosphate mannase synthase (DPMS) complex that may serve as membrane anchors for the catalytic core, DPMS1, or provide catalytic assistance. It is localized in the ER and mediates isoprenyl-linked glycan biogenesis.
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Genomic context

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Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (27948045..27951668, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene Protein kinase superfamily protein Neighboring gene Intron maturase, type II family protein Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ncRNA Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis. Jadid N, et al. Plant Cell, 2011 May. PMID 21558543, Free PMC Article
  2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In plants, Dol-P-Man is synthesized when Dol-P-Man synthase1 (DPMS1), the catalytic core, interacts with two binding proteins, DPMS2 and DPMS3, that may serve as membrane anchors for DPMS1 or provide catalytic assistance.
    Title: DOLICHOL PHOSPHATE MANNOSE SYNTHASE1 mediates the biogenesis of isoprenyl-linked glycans and influences development, stress response, and ammonium hypersensitivity in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_001334642.1
NM_106094.7

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
contributes_to dolichyl-phosphate beta-D-mannosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables enzyme regulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dolichol metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
part_of dolichol-phosphate-mannose synthase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dolichol phosphate-mannose biosynthesis regulatory protein-like protein
NP_177574.1
  • dolichol phosphate-mannose biosynthesis regulatory protein-related; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: macromolecule biosynthetic process; LOCATED IN: integral to endoplasmic reticulum membrane, endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dolichol phosphate-mannose biosynthesis regulatory (InterPro:IPR009914); Has 224 Blast hits to 224 proteins in 115 species: Archae - 0; Bacteria - 0; Metazoa - 93; Fungi - 78; Plants - 25; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    27948045..27951668 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106094.7 → NP_177574.1  dolichol phosphate-mannose biosynthesis regulatory protein-like protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177574.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9CA79
    UniProtKB/TrEMBL
    A0A5S9WUA9, A0A654EP68
    Conserved Domains (1) summary
    pfam07297
    Location:4 → 79
    DPM2; Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)

  2. NM_001334642.1 → NP_001320932.1  dolichol phosphate-mannose biosynthesis regulatory protein-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9CA79
    UniProtKB/TrEMBL
    A0A5S9WUA9, A0A654EP68
    Conserved Domains (1) summary
    pfam07297
    Location:4 → 79
    DPM2; Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CA79.1

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