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Pomt1 protein-O-mannosyltransferase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84430, updated on 30-Sep-2021

Summary

Official Symbol
Pomt1provided by RGD
Official Full Name
protein-O-mannosyltransferase 1provided by RGD
Primary source
RGD:620078
See related
EnsemblRapid:ENSRNOG00000010477
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
human homolog is mutated in patients with Walker-Warburg syndrome, a neuronal migration disorder [RGD, Feb 2006]
Expression
Biased expression in Testes (RPKM 85.2), Adrenal (RPKM 60.0) and 9 other tissues See more
Orthologs
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Genomic context

See Pomt1 in Genome Data Viewer
Location:
3p12
Exon count:
22
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (15520717..15538579)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (11253424..11271873)

Chromosome 3 - NC_051338.1Genomic Context describing neighboring genes Neighboring gene proline-rich coiled-coil 2B Neighboring gene small nucleolar RNA SNORD62 Neighboring gene uncharacterized LOC103691765 Neighboring gene small nucleolar RNA SNORD62 Neighboring gene uridine-cytidine kinase 1 Neighboring gene 60S ribosomal protein L7a-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables dolichyl-phosphate-mannose-protein mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables mannosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within extracellular matrix organization ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein O-linked glycosylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein O-linked mannosylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein O-linked mannosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in acrosomal vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein O-mannosyl-transferase 1
Names
dolichyl-phosphate-mannose--protein mannosyltransferase 1
NP_445858.1
XP_038961907.1
XP_038961908.1
XP_038961909.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053406.2NP_445858.1  protein O-mannosyl-transferase 1

    See identical proteins and their annotated locations for NP_445858.1

    Status: VALIDATED

    Source sequence(s)
    AF192388, BC070912, DY309994
    UniProtKB/Swiss-Prot
    Q99PR0
    Related
    ENSRNOP00000015214.3, ENSRNOT00000015214.5
    Conserved Domains (1) summary
    COG1928
    Location:22742
    PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051338.1 Reference mRatBN7.2 Primary Assembly

    Range
    15520717..15538579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039105980.1XP_038961908.1  protein O-mannosyl-transferase 1 isoform X2

    Related
    ENSRNOP00000073262.1, ENSRNOT00000082794.2
    Conserved Domains (1) summary
    COG1928
    Location:22692
    PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]
  2. XM_039105981.1XP_038961909.1  protein O-mannosyl-transferase 1 isoform X3

    Conserved Domains (1) summary
    COG1928
    Location:22433
    PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]
  3. XM_039105979.1XP_038961907.1  protein O-mannosyl-transferase 1 isoform X1

    Conserved Domains (1) summary
    COG1928
    Location:22742
    PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]

RNA

  1. XR_352227.3 RNA Sequence

  2. XR_005501994.1 RNA Sequence

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