U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ABLIM2 actin binding LIM protein family member 2 [ Homo sapiens (human) ]

Gene ID: 84448, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
ABLIM2provided by HGNC
Official Full Name
actin binding LIM protein family member 2provided by HGNC
Primary source
HGNC:HGNC:19195
See related
Ensembl:ENSG00000163995 MIM:612544; AllianceGenome:HGNC:19195
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in actin cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in spleen (RPKM 7.8), brain (RPKM 4.6) and 16 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
4p16.1
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (7965327..8158813, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (7943879..8137197, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (7967054..8160540, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124900656 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7806013-7806582 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7806583-7807151 Neighboring gene actin filament associated protein 1 Neighboring gene Sharpr-MPRA regulatory region 8435 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:7809617-7810117 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr4:7827707-7828208 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr4:7828209-7828708 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:7830049-7830549 Neighboring gene Sharpr-MPRA regulatory region 14367 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:7845474-7845654 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15253 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7851945-7852446 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7854640-7855140 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7884073-7884574 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:7895735-7895928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7916363-7917329 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7919591-7920401 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7920402-7921211 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:7940549-7941053 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15254 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7951399-7951898 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7957833-7958334 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7958335-7958834 Neighboring gene uncharacterized LOC389199 Neighboring gene Sharpr-MPRA regulatory region 6491 Neighboring gene uncharacterized LOC124900657 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7973234-7973789 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:7973790-7974346 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15255 Neighboring gene Sharpr-MPRA regulatory region 1176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7986340-7987294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7987295-7988247 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:7994807-7995347 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8000331-8000831 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8007792-8008380 Neighboring gene Sharpr-MPRA regulatory region 2931 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8026198-8026721 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:8026730-8027230 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8039172-8039672 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8041509-8042464 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8050961-8051572 Neighboring gene microRNA 95 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8062037-8062764 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8072999-8073862 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8080453-8080952 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8086980-8087888 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8098780-8099499 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8105045-8105756 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8105757-8106466 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8107177-8107886 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8106467-8107176 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8110453-8111188 Neighboring gene Sharpr-MPRA regulatory region 605 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8127946-8128570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8151878-8152752 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15256 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15257 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8175771-8176270 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8177753-8178598 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8189546-8190072 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8191649-8192174 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:8193227-8193751 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21281 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21282 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21283 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15258 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21284 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21286 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21288 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8207619-8208120 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8208121-8208620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8210744-8211508 Neighboring gene guanine monophosphate synthase pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8217127-8217691 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8217692-8218255 Neighboring gene SH3 domain and tetratricopeptide repeats 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8228681-8229350 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21291 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8230692-8231362 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8239598-8240458 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:8240459-8241317

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genomic organisation and tissue specific expression of ABLIM2 gene in human, mouse and rat. Klimov E, et al. Biochim Biophys Acta, 2005 Jul 25. PMID 16005990
  2. Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin. Barrientos T, et al. J Biol Chem, 2007 Mar 16. PMID 17194709
  3. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Nagase T, et al. DNA Res, 2001 Apr 27. PMID 11347906
  4. A human MAP kinase interactome. Bandyopadhyay S, et al. Nat Methods, 2010 Oct. PMID 20936779, Free PMC Article
  5. A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. Blandin G, et al. Skelet Muscle, 2013 Feb 15. PMID 23414517, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • FLJ26534, FLJ39684, KIAA1808, MGC141918, DKFZp761F129

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in actin cytoskeleton IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
actin-binding LIM protein 2
Names
abLIM-2
testis tissue sperm-binding protein Li 35a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130083.2 → NP_001123555.1  actin-binding LIM protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AJ748601, AK094798, AK097003, BC067214, BE155865, BQ267829
    Consensus CDS
    CCDS47014.1
    UniProtKB/TrEMBL
    A0A140VK02, Q19VH1
    Related
    ENSP00000393511.2, ENST00000447017.7
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:611 → 645
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 609
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  2. NM_001130084.2 → NP_001123556.1  actin-binding LIM protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001123556.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the mid-coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AJ748601, AK097003, BC067214, BQ267829
    Consensus CDS
    CCDS47013.1
    UniProtKB/Swiss-Prot
    E9PF39, Q08E71, Q19VH0, Q6H8Q0, Q6H8Q1, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7
    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000342813.5, ENST00000341937.9
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:577 → 611
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 575
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  3. NM_001130085.2 → NP_001123557.1  actin-binding LIM protein 2 isoform 3

    See identical proteins and their annotated locations for NP_001123557.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice site in the mid-coding region, and lacks a segment in the 3' coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AJ748600, AK097003, BC067214, BQ267829
    Consensus CDS
    CCDS47012.1
    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000355003.5, ENST00000361581.9
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:538 → 572
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 536
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  4. NM_001130086.2 → NP_001123558.1  actin-binding LIM protein 2 isoform 4

    See identical proteins and their annotated locations for NP_001123558.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame segment and uses an alternate in-frame splice site in the mid-coding region, compared to variant 1. The resulting isoform (4) is shorter than isoform 1.
    Source sequence(s)
    AJ748601, AK097003, BC067214, BQ267829, DQ413177
    Consensus CDS
    CCDS47011.1
    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000421283.1, ENST00000505872.5
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:525 → 559
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 523
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  5. NM_001130087.2 → NP_001123559.1  actin-binding LIM protein 2 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) includes an alternate in-frame exon and uses an alternate in-frame splice site in the mid-coding region, and lacks alternate in-frame segments in both the mid- and 3' coding regions, compared to variant 1. The resulting isoform (5) is shorter than isoform 1.
    Source sequence(s)
    AK094754, AK094798, AK097003, BC067214, BQ267829
    Consensus CDS
    CCDS47015.1
    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000354887.5, ENST00000361737.9
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:497 → 531
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 495
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  6. NM_001130088.2 → NP_001123560.1  actin-binding LIM protein 2 isoform 7

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 3' UTR, includes an alternate in-frame exon and lacks an alternate in-frame segment in the mid-coding region, and lacks several exons in the 3' coding region, compared to variant 1. The resulting isoform (7) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK094798, BC067214, BM718728
    Consensus CDS
    CCDS47016.1
    UniProtKB/TrEMBL
    B7Z6W4
    Related
    ENSP00000389410.2, ENST00000428004.6
    Conserved Domains (5) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:277 → 428
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  7. NM_001286688.2 → NP_001273617.1  actin-binding LIM protein 2 isoform 8

    See identical proteins and their annotated locations for NP_001273617.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and coding sequence, contains an alternate in-frame exon, and lacks an alternate in-frame segment compared to variant 1. The resulting isoform (8) is shorter at the N-terminus, lacks an alternate segment, and contains another alternate segment compared to isoform 1.
    Source sequence(s)
    AK094798, AK097003, BQ267829, DA392726
    Consensus CDS
    CCDS68669.1
    UniProtKB/Swiss-Prot
    Q6H8Q1
    Related
    ENSP00000423661.1, ENST00000514025.5
    Conserved Domains (3) summary
    pfam02209
    Location:312 → 346
    VHP; Villin headpiece domain
    pfam16182
    Location:34 → 310
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:1 → 24
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  8. NM_032432.5 → NP_115808.3  actin-binding LIM protein 2 isoform 6

    See identical proteins and their annotated locations for NP_115808.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks alternate in-frame segments in both the mid- and 3' coding regions, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.
    Source sequence(s)
    AK094798, AK097003, BC067214, BC122567, BQ267829
    Consensus CDS
    CCDS54719.1
    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000384658.3, ENST00000407564.7
    Conserved Domains (6) summary
    cd09327
    Location:24 → 75
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80 → 135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153 → 204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212 → 267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:487 → 521
    VHP; Villin headpiece domain
    pfam16182
    Location:277 → 485
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    7965327..8158813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047416308.1 → XP_047272264.1  actin-binding LIM protein 2 isoform X12

  2. XM_047416301.1 → XP_047272257.1  actin-binding LIM protein 2 isoform X5

    Related
    ENSP00000518527.1, ENST00000710854.1

  3. XM_047416299.1 → XP_047272255.1  actin-binding LIM protein 2 isoform X3

  4. XM_005248030.5 → XP_005248087.1  actin-binding LIM protein 2 isoform X40

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:491 → 525
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 489
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  5. XM_005248027.5 → XP_005248084.1  actin-binding LIM protein 2 isoform X34

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:530 → 564
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 528
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  6. XM_005248029.5 → XP_005248086.1  actin-binding LIM protein 2 isoform X38

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:492 → 526
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 490
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  7. XM_005248024.5 → XP_005248081.1  actin-binding LIM protein 2 isoform X32

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:543 → 577
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 541
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  8. XM_005248022.5 → XP_005248079.1  actin-binding LIM protein 2 isoform X28

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Related
    ENSP00000504601.1, ENST00000676532.1
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:582 → 616
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 580
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  9. XM_047416307.1 → XP_047272263.1  actin-binding LIM protein 2 isoform X11

  10. XM_047416306.1 → XP_047272262.1  actin-binding LIM protein 2 isoform X10

  11. XM_017008715.3 → XP_016864204.1  actin-binding LIM protein 2 isoform X31

    UniProtKB/TrEMBL
    Q19VH1

  12. XM_005248023.5 → XP_005248080.1  actin-binding LIM protein 2 isoform X29

    UniProtKB/TrEMBL
    Q19VH1
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:576 → 610
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 574
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  13. XM_005248020.5 → XP_005248077.1  actin-binding LIM protein 2 isoform X22

    UniProtKB/TrEMBL
    Q19VH1
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:615 → 649
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 613
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  14. XM_047416310.1 → XP_047272266.1  actin-binding LIM protein 2 isoform X14

  15. XM_005248019.5 → XP_005248076.1  actin-binding LIM protein 2 isoform X21

    UniProtKB/TrEMBL
    F5GYR0, Q19VH1
    Related
    ENSP00000441255.3, ENST00000545242.6
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:616 → 650
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 614
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  16. XM_047416309.1 → XP_047272265.1  actin-binding LIM protein 2 isoform X13

  17. XM_047416300.1 → XP_047272256.1  actin-binding LIM protein 2 isoform X4

  18. XM_006713927.4 → XP_006713990.1  actin-binding LIM protein 2 isoform X37

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:502 → 536
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 500
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  19. XM_017008720.3 → XP_016864209.1  actin-binding LIM protein 2 isoform X33

    UniProtKB/TrEMBL
    A0A7I2V5G9

  20. XM_005248028.6 → XP_005248085.1  actin-binding LIM protein 2 isoform X36

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:503 → 537
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 501
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  21. XM_047416316.1 → XP_047272272.1  actin-binding LIM protein 2 isoform X30

  22. XM_047416311.1 → XP_047272267.1  actin-binding LIM protein 2 isoform X15

  23. XM_047416313.1 → XP_047272269.1  actin-binding LIM protein 2 isoform X17

  24. XM_047416312.1 → XP_047272268.1  actin-binding LIM protein 2 isoform X16

  25. XM_047416302.1 → XP_047272258.1  actin-binding LIM protein 2 isoform X6

  26. XM_006713925.4 → XP_006713988.1  actin-binding LIM protein 2 isoform X25

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:587 → 621
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 585
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  27. XM_006713924.5 → XP_006713987.1  actin-binding LIM protein 2 isoform X20

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:626 → 660
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 624
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  28. XM_047416305.1 → XP_047272261.1  actin-binding LIM protein 2 isoform X9

  29. XM_005248021.6 → XP_005248078.1  actin-binding LIM protein 2 isoform X24

    UniProtKB/TrEMBL
    A0A7I2V5G9
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:588 → 622
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 586
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  30. XM_047416303.1 → XP_047272259.1  actin-binding LIM protein 2 isoform X7

  31. XM_006713923.5 → XP_006713986.1  actin-binding LIM protein 2 isoform X19

    UniProtKB/TrEMBL
    A0AA34QVK8
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:627 → 661
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 625
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  32. XM_047416298.1 → XP_047272254.1  actin-binding LIM protein 2 isoform X2

  33. XM_005248017.5 → XP_005248074.1  actin-binding LIM protein 2 isoform X18

    UniProtKB/TrEMBL
    A0AA34QVK8
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:628 → 662
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 626
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  34. XM_005248014.6 → XP_005248071.1  actin-binding LIM protein 2 isoform X8

    UniProtKB/TrEMBL
    A0AA34QVK8
    Conserved Domains (6) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:667 → 701
    VHP; Villin headpiece domain
    pfam16182
    Location:282 → 665
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  35. XM_047416297.1 → XP_047272253.1  actin-binding LIM protein 2 isoform X1

  36. XM_047416315.1 → XP_047272271.1  actin-binding LIM protein 2 isoform X27

  37. XM_047416314.1 → XP_047272270.1  actin-binding LIM protein 2 isoform X26

  38. XM_011513586.4 → XP_011511888.1  actin-binding LIM protein 2 isoform X23

    UniProtKB/TrEMBL
    A0AA34QVK8
    Conserved Domains (5) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:282 → 472
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

  39. XM_047416318.1 → XP_047272274.1  actin-binding LIM protein 2 isoform X43

  40. XM_017008725.2 → XP_016864214.1  actin-binding LIM protein 2 isoform X42

    UniProtKB/TrEMBL
    B7Z6W4

  41. XM_047416317.1 → XP_047272273.1  actin-binding LIM protein 2 isoform X39

  42. XM_017008723.2 → XP_016864212.1  actin-binding LIM protein 2 isoform X35

    UniProtKB/TrEMBL
    Q19VH1

  43. XM_005248031.5 → XP_005248088.1  actin-binding LIM protein 2 isoform X41

    UniProtKB/TrEMBL
    B7Z6W4
    Conserved Domains (5) summary
    cd09327
    Location:29 → 80
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85 → 140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158 → 209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217 → 272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:282 → 433
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    7943879..8137197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054351058.1 → XP_054207033.1  actin-binding LIM protein 2 isoform X12

  2. XM_054351051.1 → XP_054207026.1  actin-binding LIM protein 2 isoform X5

  3. XM_054351049.1 → XP_054207024.1  actin-binding LIM protein 2 isoform X3

  4. XM_054351078.1 → XP_054207053.1  actin-binding LIM protein 2 isoform X1

  5. XM_054351061.1 → XP_054207036.1  actin-binding LIM protein 2 isoform X15

  6. XM_054351052.1 → XP_054207027.1  actin-binding LIM protein 2 isoform X6

  7. XM_054351048.1 → XP_054207023.1  actin-binding LIM protein 2 isoform X2

  8. XM_054351057.1 → XP_054207032.1  actin-binding LIM protein 2 isoform X11

  9. XM_054351056.1 → XP_054207031.1  actin-binding LIM protein 2 isoform X10

  10. XM_054351050.1 → XP_054207025.1  actin-binding LIM protein 2 isoform X4

  11. XM_054351063.1 → XP_054207038.1  actin-binding LIM protein 2 isoform X17

  12. XM_054351062.1 → XP_054207037.1  actin-binding LIM protein 2 isoform X16

  13. XM_054351055.1 → XP_054207030.1  actin-binding LIM protein 2 isoform X9

  14. XM_054351053.1 → XP_054207028.1  actin-binding LIM protein 2 isoform X7

  15. XM_054351060.1 → XP_054207035.1  actin-binding LIM protein 2 isoform X14

  16. XM_054351059.1 → XP_054207034.1  actin-binding LIM protein 2 isoform X13

  17. XM_054351066.1 → XP_054207041.1  actin-binding LIM protein 2 isoform X20

  18. XM_054351065.1 → XP_054207040.1  actin-binding LIM protein 2 isoform X19

  19. XM_054351064.1 → XP_054207039.1  actin-binding LIM protein 2 isoform X18

  20. XM_054351054.1 → XP_054207029.1  actin-binding LIM protein 2 isoform X8

  21. XM_054351074.1 → XP_054207049.1  actin-binding LIM protein 2 isoform X28

  22. XM_054351068.1 → XP_054207043.1  actin-binding LIM protein 2 isoform X22

  23. XM_054351067.1 → XP_054207042.1  actin-binding LIM protein 2 isoform X21

    UniProtKB/TrEMBL
    F5GYR0

  24. XM_054351080.1 → XP_054207055.1  actin-binding LIM protein 2 isoform X33

  25. XM_054351076.1 → XP_054207051.1  actin-binding LIM protein 2 isoform X30

  26. XM_054351071.1 → XP_054207046.1  actin-binding LIM protein 2 isoform X25

  27. XM_054351070.1 → XP_054207045.1  actin-binding LIM protein 2 isoform X24

  28. XM_054351081.1 → XP_054207056.1  actin-binding LIM protein 2 isoform X34

  29. XM_054351079.1 → XP_054207054.1  actin-binding LIM protein 2 isoform X32

  30. XM_054351077.1 → XP_054207052.1  actin-binding LIM protein 2 isoform X31

  31. XM_054351075.1 → XP_054207050.1  actin-binding LIM protein 2 isoform X29

  32. XM_054351084.1 → XP_054207059.1  actin-binding LIM protein 2 isoform X37

  33. XM_054351083.1 → XP_054207058.1  actin-binding LIM protein 2 isoform X36

  34. XM_054351087.1 → XP_054207062.1  actin-binding LIM protein 2 isoform X40

  35. XM_054351085.1 → XP_054207060.1  actin-binding LIM protein 2 isoform X38

  36. XM_054351069.1 → XP_054207044.1  actin-binding LIM protein 2 isoform X23

  37. XM_054351073.1 → XP_054207048.1  actin-binding LIM protein 2 isoform X27

  38. XM_054351072.1 → XP_054207047.1  actin-binding LIM protein 2 isoform X26

  39. XM_054351090.1 → XP_054207065.1  actin-binding LIM protein 2 isoform X43

  40. XM_054351089.1 → XP_054207064.1  actin-binding LIM protein 2 isoform X42

  41. XM_054351086.1 → XP_054207061.1  actin-binding LIM protein 2 isoform X39

  42. XM_054351082.1 → XP_054207057.1  actin-binding LIM protein 2 isoform X35

  43. XM_054351088.1 → XP_054207063.1  actin-binding LIM protein 2 isoform X41

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6H8Q1.2 GenPept UniProtKB/Swiss-Prot:Q6H8Q1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous