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TMEM276 transmembrane protein 276 [ Homo sapiens (human) ]

Gene ID: 84773, updated on 23-Mar-2024

Summary

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Official Symbol
TMEM276provided by HGNC
Official Full Name
transmembrane protein 276provided by HGNC
Primary source
HGNC:HGNC:56235
See related
Ensembl:ENSG00000291317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
mouse all
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Genomic context

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See TMEM276 in Genome Data Viewer
Location:
8q24.3
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (144463825..144467015, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (145633585..145636756, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (145689208..145691084, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene tonsoku like, DNA repair protein Neighboring gene TONSL antisense RNA 1 Neighboring gene microRNA 6893 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145668715-145669223 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19685 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19686 Neighboring gene TMEM276-ZFTRAF1 readthrough Neighboring gene zinc finger TRAF-type containing 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145687825-145688502 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145688503-145689180 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145689275-145689888 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19689 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19690 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19691 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19692 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145692087-145692923 Neighboring gene microRNA 10400 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19695 Neighboring gene kinesin family member C2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145698787-145699682 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145699683-145700576 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145701473-145702366 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19696 Neighboring gene forkhead box H1 Neighboring gene protein phosphatase 1 regulatory subunit 16A Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145709653-145710352 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145710353-145711052 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:145715271-145715770 Neighboring gene uncharacterized LOC101928953 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:145725199-145725860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19697

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

General gene information

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Readthrough TMEM276-ZFTRAF1

Readthrough gene: TMEM276-ZFTRAF1, Included gene: ZFTRAF1

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 276

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001129888.2 → NP_001123360.1  transmembrane protein 276 precursor

    See identical proteins and their annotated locations for NP_001123360.1

    Status: VALIDATED

    Source sequence(s)
    AC084125
    Consensus CDS
    CCDS6426.1
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6
    Related
    ENSP00000414647.2, ENST00000424149.6

  2. NM_001408058.1 → NP_001394987.1  transmembrane protein 276 precursor

    Status: VALIDATED

    Source sequence(s)
    AC084125
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6
    Related
    ENSP00000385962.2, ENST00000403000.6

  3. NM_001408059.1 → NP_001394988.1  transmembrane protein 276 precursor

    Status: VALIDATED

    Source sequence(s)
    AC084125
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6

  4. NM_001408060.1 → NP_001394989.1  transmembrane protein 276 precursor

    Status: VALIDATED

    Source sequence(s)
    AC084125
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6

  5. NM_001408061.1 → NP_001394990.1  transmembrane protein 276 precursor

    Status: VALIDATED

    Source sequence(s)
    AC084125
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6

  6. NM_001408062.1 → NP_001394991.1  transmembrane protein 276 precursor

    Status: VALIDATED

    Source sequence(s)
    AC084125
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6

  7. NM_032687.4 → NP_116076.1  transmembrane protein 276 precursor

    See identical proteins and their annotated locations for NP_116076.1

    Status: VALIDATED

    Source sequence(s)
    AC084125, BC005073, BC056412, BM671891
    UniProtKB/Swiss-Prot
    B3KSX0, D3DWM3, P0DTL5, Q6ZMK1, Q9BSF6, Q9BSU6
    Related
    ENSP00000304826.5, ENST00000306145.10

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    144463825..144467015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    145633585..145636756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DTL5.1 GenPept UniProtKB/Swiss-Prot:P0DTL5

Gene LinkOut

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