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ATG33 Atg33p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851070, updated on 17-May-2024

Summary

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Gene symbol
ATG33
Gene description
Atg33p
Primary source
FungiDB:YLR356W
Locus tag
YLR356W
See related
SGD:S000004348; AllianceGenome:SGD:S000004348
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in autophagy of mitochondrion and macroautophagy. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ATG33 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (840321..840914)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate transaldolase TAL1 Neighboring gene ketol-acid reductoisomerase Neighboring gene Rsc2p Neighboring gene uncharacterized protein Neighboring gene adenylosuccinase ADE13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial depolarization in yeast zygotes inhibits clonal expansion of selfish mtDNA. Karavaeva IE, et al. J Cell Sci, 2017 Apr 1. PMID 28193734
  2. Uth1 is a mitochondrial inner membrane protein dispensable for post-log-phase and rapamycin-induced mitophagy. Welter E, et al. FEBS J, 2013 Oct. PMID 23910823
  3. A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast. Wang CW, et al. J Cell Biol, 2014 Aug 4. PMID 25070953, Free PMC Article
  4. Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response. Guerra-Moreno A, et al. J Biol Chem, 2015 Dec 11. PMID 26491016, Free PMC Article
  5. Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Díaz-Mejía JJ, et al. Mol Syst Biol, 2018 May 28. PMID 29807908, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in autophagy of mitochondrion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in macroautophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Atg33p
NP_013460.1
  • Mitochondrial mitophagy-specific protein; required primarily for mitophagy induced at post-log phase; not required for other types of selective autophagy or macroautophagy; conserved within fungi, but not in higher eukaryotes; ATG33 has a paralog, SCM4, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    840321..840914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182245.1 → NP_013460.1  TPA: Atg33p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013460.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A7A1N4, B3RHM5, C7GRY1, C8ZDW3, D6VYZ4, Q06485
    UniProtKB/TrEMBL
    A0A8H4BZ04, N1P782
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06485.1

Gene LinkOut

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