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FBP1 fructose 1,6-bisphosphate 1-phosphatase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851092, updated on 4-Aug-2021

Summary

Gene symbol
FBP1
Gene description
fructose 1,6-bisphosphate 1-phosphatase
Primary source
SGD:S000004369
Locus tag
YLR377C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ACN8
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Genomic context

See FBP1 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (873746..874792, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Stp3p Neighboring gene Psy3p Neighboring gene tRNA Neighboring gene translocon subunit SEC61

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the FBP1 gene: The FBP1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables fructose 1,6-bisphosphate 1-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables fructose 1,6-bisphosphate 1-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables fructose 1,6-bisphosphate 1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables fructose 1,6-bisphosphate 1-phosphatase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in fructose 1,6-bisphosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in fructose 6-phosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in fructose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in gluconeogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in sucrose biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
fructose 1,6-bisphosphate 1-phosphatase
NP_013481.3
  • Fructose-1,6-bisphosphatase; key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; glucose starvation results in redistribution to the periplasm; interacts with Vid30p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    873746..874792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182266.3NP_013481.3  TPA: fructose 1,6-bisphosphate 1-phosphatase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013481.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P09201
    Conserved Domains (1) summary
    COG0158
    Location:20348
    Fbp; Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]
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