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SEC31 Sec31p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851332, updated on 13-Apr-2024

Summary

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Gene symbol
SEC31
Gene description
Sec31p
Primary source
SGD:S000002354
Locus tag
YDL195W
See related
AllianceGenome:SGD:S000002354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
WEB1
Summary
Enables structural molecule activity. Involved in COPII-coated vesicle budding. Located in mating projection tip. Part of COPII vesicle coat. Orthologous to several human genes including SEC31A (SEC31 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (107208..111029)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ggc1p Neighboring gene Asf2p Neighboring gene glucose sensor Neighboring gene ditrans,polycis-polyprenyl diphosphate synthase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast. Bednarek SY, et al. Cell, 1995 Dec 29. PMID 8548805
  2. Involvement of the penta-EF-hand protein Pef1p in the Ca2+-dependent regulation of COPII subunit assembly in Saccharomyces cerevisiae. Yoshibori M, et al. PLoS One, 2012. PMID 22792405, Free PMC Article
  3. Structure and organization of coat proteins in the COPII cage. Fath S, et al. Cell, 2007 Jun 29. PMID 17604721
  4. New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex. Wuestehube LJ, et al. Genetics, 1996 Feb. PMID 8852839, Free PMC Article
  5. Suppression of mutations in two Saccharomyces cerevisiae genes by the adenovirus E1A protein. Zieler HA, et al. Mol Cell Biol, 1995 Jun. PMID 7760818, Free PMC Article

See all (102) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in COPII-coated vesicle budding IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in COPII-coated vesicle budding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in COPII-coated vesicle cargo loading IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of COPII vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of COPII vesicle coat IDA
Inferred from Direct Assay
more info
 PubMed 
located_in ER to Golgi transport vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mating projection tip HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sec31p
NP_010086.2
  • Component of the Sec13p-Sec31p complex of the COPII vesicle coat; COPII coat is required for vesicle formation in ER to Golgi transport; mutant has increased aneuploidy tolerance

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    107208..111029
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180255.2 → NP_010086.2  TPA: Sec31p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010086.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRF8, P38968
    UniProtKB/TrEMBL
    A0A8H8UMA5, B3LH77, B5VF81, C8Z6A8, G2WBX1
    Conserved Domains (4) summary
    PHA03247
    Location:772 → 1172
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:12 → 61
    7WD40; WD40 repeat [structural motif]
    pfam11549
    Location:899 → 946
    Sec31; Protein transport protein SEC31
    cl29593
    Location:17 → 327
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
6ZL0_A.1
6ZL0_C.1
P38968.3

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