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RRP1 Rrp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851660, updated on 17-May-2024

Summary

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Gene symbol
RRP1
Gene description
Rrp1p
Primary source
FungiDB:YDR087C
Locus tag
YDR087C
See related
SGD:S000002494; AllianceGenome:SGD:S000002494; VEuPathDB:YDR087C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in rRNA processing. Located in nucleolus. Part of preribosome, large subunit precursor. Orthologous to human RRP1 (ribosomal RNA processing 1) and RRP1B (ribosomal RNA processing 1B). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RRP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (617470..618306, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Afr1p Neighboring gene translocon subunit SSS1 Neighboring gene mRNA splicing protein SLU7 Neighboring gene tRNA-Arg

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RRP1, a Saccharomyces cerevisiae gene affecting rRNA processing and production of mature ribosomal subunits. Fabian GR, et al. J Bacteriol, 1987 Apr. PMID 3549696, Free PMC Article
  2. SRD1, a S. cerevisiae gene affecting pre-rRNA processing contains a C2/C2 zinc finger motif. Hess SM, et al. Nucleic Acids Res, 1994 Apr 11. PMID 8165142, Free PMC Article
  3. srd1, a Saccharomyces cerevisiae suppressor of the temperature-sensitive pre-rRNA processing defect of rrp1-1. Fabian GR, et al. Genetics, 1990 Mar. PMID 2179050, Free PMC Article
  4. Rrb1p, a yeast nuclear WD-repeat protein involved in the regulation of ribosome biosynthesis. Iouk TL, et al. Mol Cell Biol, 2001 Feb. PMID 11158312, Free PMC Article
  5. Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation. Copela LA, et al. RNA, 2008 Jun. PMID 18456844, Free PMC Article

See all (79) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor HDA PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of preribosome, small subunit precursor IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rrp1p
NP_010372.3
  • Essential evolutionarily conserved nucleolar protein; necessary for biogenesis of 60S ribosomal subunits and for processing of pre-rRNAs to mature rRNA; associated with several distinct 66S pre-ribosomal particles

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    617470..618306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180395.3 → NP_010372.3  TPA: Rrp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010372.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS74, P35178
    UniProtKB/TrEMBL
    A0A8H8UN04, A6ZY53, B3LGI4, B5VFY3, C7GVP9, C8Z505, N1P6A0
    Conserved Domains (1) summary
    pfam05997
    Location:4 → 244
    Nop52; Nucleolar protein,Nop52
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
5Z3G_X.1
6EM1_4.1
6EM3_4.1
6EM4_4.1
6EM5_4.1
7OHS_4.1
7OHW_4.1
7OHX_4.1
P35178.2

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