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SOD1 superoxide dismutase SOD1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 853568, updated on 9-Jun-2019

Summary

Gene symbol
SOD1
Gene description
superoxide dismutase SOD1
Primary source
SGD:S000003865
Locus tag
YJR104C
Gene type
protein coding
RNA name
superoxide dismutase SOD1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CRS4

Genomic context

See SOD1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (622550..623014, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ESCRT-II subunit protein VPS25 Neighboring gene CTP synthase URA8 Neighboring gene adenosine kinase Neighboring gene Ecm27p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SOD1 gene: The SOD1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
antioxidant activity IEA
Inferred from Electronic Annotation
more info
 
copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
superoxide dismutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
superoxide dismutase activity IDA
Inferred from Direct Assay
more info
PubMed 
superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
superoxide dismutase SOD1
NP_012638.1
  • Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    622550..623014 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181762.1NP_012638.1  TPA: superoxide dismutase SOD1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012638.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P00445
    Conserved Domains (1) summary
    pfam00080
    Location:10150
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
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