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PMT4 dolichyl-phosphate-mannose-protein mannosyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853608, updated on 5-Sep-2021

Summary

Gene symbol
PMT4
Gene description
dolichyl-phosphate-mannose-protein mannosyltransferase
Primary source
SGD:S000003904
Locus tag
YJR143C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See PMT4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (698326..700614, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene putative polyadenylation protein Neighboring gene uncharacterized protein Neighboring gene Mgm101p Neighboring gene ribosomal 40S subunit protein S4A

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the PMT4 gene: The PMT4 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Process Evidence Code Pubs
involved_in protein O-linked glycosylation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein O-linked glycosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein O-linked mannosylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein O-linked mannosylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of endoplasmic reticulum unfolded protein response IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dolichyl-phosphate-mannose-protein mannosyltransferase
NP_012677.1
  • Protein O-mannosyltransferase; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    698326..700614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181801.1NP_012677.1  TPA: dolichyl-phosphate-mannose-protein mannosyltransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012677.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P46971
    Conserved Domains (1) summary
    COG1928
    Location:32755
    PMT1; Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]
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