YOR142W-B gag-pol fusion protein [Saccharomyces cerevisiae S288C] - Gene

Summary

Gene symbol: YOR142W-B
Gene description: gag-pol fusion protein
Primary source: SGD:S000007352
Locus tag: YOR142W-B
See related: AllianceGenome:SGD:S000007352
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable several functions, including DNA polymerase activity; peptidase activity; and ribonuclease activity. Predicted to be involved in transposition, RNA-mediated. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-directed DNA polymerase activity	IEA Inferred from Electronic Annotation more info
enables DNA-directed DNA polymerase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA nuclease activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables RNA-DNA hybrid ribonuclease activity	IEA Inferred from Electronic Annotation more info
enables RNA-directed DNA polymerase activity	IEA Inferred from Electronic Annotation more info
enables RNA-directed DNA polymerase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables aspartic-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
enables endonuclease activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables peptidase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables zinc ion binding	RCA inferred from Reviewed Computational Analysis more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in DNA integration	IEA Inferred from Electronic Annotation more info
involved_in DNA recombination	IEA Inferred from Electronic Annotation more info
involved_in RNA-templated DNA biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in retrotransposition	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in transposition	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in retrotransposon nucleocapsid	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NP_058183.1

Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes

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