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Ddx52 DExD-box helicase 52 [ Rattus norvegicus (Norway rat) ]

Gene ID: 85432, updated on 30-Sep-2021

Summary

Official Symbol
Ddx52provided by RGD
Official Full Name
DExD-box helicase 52provided by RGD
Primary source
RGD:621743
See related
EnsemblRapid:ENSRNOG00000002612
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rok1
Summary
may act as an RNA helicase; yeast homolog is required for ribosomal RNA processing [RGD, Feb 2006]
Expression
Biased expression in Thymus (RPKM 134.7), Spleen (RPKM 108.2) and 9 other tissues See more
Orthologs
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Genomic context

See Ddx52 in Genome Data Viewer
Location:
10q26
Exon count:
15
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (68824594..68847400)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (71253667..71276397)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene HEAT repeat containing 6 Neighboring gene HNF1 homeobox B Neighboring gene synergin, gamma Neighboring gene hCG1994130-like Neighboring gene dual specificity phosphatase 14

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA helicase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in rRNA processing TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable ATP-dependent RNA helicase DDX52
Names
ATP-dependent, RNA helicase
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DEAD box protein 52
DEAD-box helicase 52
rROK1L
NP_445977.1
XP_038942927.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053525.1NP_445977.1  probable ATP-dependent RNA helicase DDX52

    See identical proteins and their annotated locations for NP_445977.1

    Status: PROVISIONAL

    Source sequence(s)
    AB055628
    UniProtKB/Swiss-Prot
    Q99PT0
    Related
    ENSRNOP00000003600.3, ENSRNOT00000003600.7
    Conserved Domains (3) summary
    PRK11192
    Location:163591
    PRK11192; ATP-dependent RNA helicase SrmB; Provisional
    pfam00271
    Location:399508
    Helicase_C; Helicase conserved C-terminal domain
    cl21455
    Location:170376
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    68824594..68847400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086999.1XP_038942927.1  probable ATP-dependent RNA helicase DDX52 isoform X1

    Related
    ENSRNOP00000083648.1, ENSRNOT00000119012.1
    Conserved Domains (2) summary
    COG0513
    Location:137574
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd17957
    Location:177378
    DEADc_DDX52; DEAD-box helicase domain of DEAD box protein 52
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