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SPT15 TATA-binding protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 856891, updated on 18-Nov-2018

Summary

Gene symbol
SPT15
Gene description
TATA-binding protein
Primary source
SGD:S000000950
Locus tag
YER148W
Gene type
protein coding
RNA name
TATA-binding protein
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
BTF1; TBP1

Genomic context

See SPT15 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (465303..466025)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene RNA-binding protein LSM5 Neighboring gene cohesin-loading factor complex subunit SCC4 Neighboring gene Pea2p Neighboring gene Spi1p

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SPT15 gene: The SPT15 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding, bending IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase I transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase I transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase I transcription regulator recruiting activity IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase I transcription regulator recruiting activity IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II activating transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II activating transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II core promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II core promoter sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II general transcription initiation factor activity IC
Inferred by Curator
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase III general transcription initiation factor activity IC
Inferred by Curator
more info
 
RNA polymerase III regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase III regulatory region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding HDA PubMed 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA-templated transcription, initiation IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase I preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II preinitiation complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
RNA polymerase III preinitiation complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase III preinitiation complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
nucleolar large rRNA transcription by RNA polymerase I IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transposon integration IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor TFIID complex IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor TFIIIB complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor TFIIIB complex IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
TATA-binding protein
NP_011075.3
  • TATA-binding protein (TBP); general transcription factor that interacts with other factors to form the preinitiation complex at promoters; essential for viability, highly conserved; yeast gene can complement mutations in human homolog TBP

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    465303..466025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179038.3NP_011075.3  TPA: TATA-binding protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011075.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P13393
    Conserved Domains (1) summary
    PLN00062
    Location:64239
    PLN00062; TATA-box-binding protein; Provisional
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