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mhcA myosin II heavy chain [ Dictyostelium discoideum AX4 ]

Gene ID: 8625606, updated on 28-Oct-2021

Summary

Gene symbol
mhcA
Gene description
myosin II heavy chain
Primary source
dictyBase:DDB_G0286355
Locus tag
DDB_G0286355
Gene type
protein coding
RNA name
myosin II heavy chain
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium
Old locus tag
DDBDRAFT_0186963; DDBDRAFT_0191444; DDB_0186963; DDB_0191444
NEW
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Genomic context

Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_007090.3 (4451077..4457427)

Chromosome 4 - NC_007090.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene WD40 repeat-containing protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 14-3-3 protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IDA
Inferred from Direct Assay
more info
PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 
enables adenyl nucleotide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables calcium-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
enables cytoskeletal motor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables microfilament motor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in actin-myosin filament sliding IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within aggregation involved in sorocarp development IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within bleb assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell motility IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cell motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within contractile actin filament bundle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within contractile vacuole organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cortical actin cytoskeleton organization IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within culmination involved in sorocarp development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cytoplasmic actin-based contraction involved in forward cell motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within detection of mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within filopodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within hypotonic response IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within mitotic cytokinesis IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in myosin filament assembly IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within pseudopodium retraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of cell shape IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to cAMP IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within response to differentiation-inducing factor 1 HDA PubMed 
involved_in response to hydrogen peroxide IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within response to mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within uropod retraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in actomyosin IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in actomyosin contractile ring IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in apical cortex IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cell trailing edge IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cleavage furrow IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cortical actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in early phagosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in equatorial cell cortex IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular matrix HDA PubMed 
part_of myosin II complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in myosin filament IDA
Inferred from Direct Assay
more info
PubMed 
located_in phagocytic cup base IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in pseudopodium IDA
Inferred from Direct Assay
more info
PubMed 
located_in uropod IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Names
myosin II heavy chain
myosin heavy chain

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007090.3 Reference assembly

    Range
    4451077..4457427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_632648.1XP_637740.1  myosin II heavy chain [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_637740.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P08799
    Conserved Domains (6) summary
    cd01377
    Location:100747
    MYSc_class_II; class II myosins, motor domain
    pfam00063
    Location:88747
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:10372018
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:3373
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam06273
    Location:12881368
    eIF-4B; Plant specific eukaryotic initiation factor 4B
    pfam15743
    Location:13471495
    SPATA1_C; Spermatogenesis-associated C-terminus
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