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CG40472 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 8673970, updated on 10-May-2024

Summary

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Official Symbol
CG40472provided by FlyBase
Primary source
FLYBASE:FBgn0085736
Locus tag
Dmel_CG40472
See related
AllianceGenome:FB:FBgn0085736
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CR40472; Dmel\CG40472; dNDUFB2B; ND-AGGGL; NDUFB2
Summary
Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in adult head. Orthologous to human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG40472 in Genome Data Viewer
Location:
80F9-80F9; 3-47 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (24927130..24927710)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3LHet NW_001848857.1 (410462..411042)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene scarecrow Neighboring gene long non-coding RNA:CR46483 Neighboring gene NADH dehydrogenase (ubiquinone) AGGG subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Paternal diet affects differential gene expression, but not sperm competition, in sons. Zajitschek F, et al. Biol Lett, 2017 Feb. PMID 28202685, Free PMC Article
  2. The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster. Hossain KFB, et al. Sci Rep, 2022 Dec 27. PMID 36575244, Free PMC Article
  3. Genetic and Molecular Analysis of Essential Genes in Centromeric Heterochromatin of the Left Arm of Chromosome 3 in Drosophila melanogaster. Syrzycka M, et al. G3 (Bethesda), 2019 May 7. PMID 30948422, Free PMC Article
  4. Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Agip AA, et al. Elife, 2023 Jan 9. PMID 36622099, Free PMC Article
  5. Insights from Drosophila on mitochondrial complex I. Rhooms SK, et al. Cell Mol Life Sci, 2020 Feb. PMID 31485716, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex I IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial respiratory chain complex I IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial respiratory chain complex I ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG40472-PC
NADH dehydrogenase (ubiquinone) AGGG subunit-like

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    24927130..24927710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170374.1 → NP_001163845.1  uncharacterized protein Dmel_CG40472 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163845.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7PL91
    Conserved Domains (1) summary
    pfam14813
    Location:26 → 93
    NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7PL91 Q7PL91

Gene LinkOut

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