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Xport-B exit protein of rhodopsin and TRP B [ Drosophila melanogaster (fruit fly) ]

Gene ID: 8673993, updated on 10-May-2024

Summary

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Official Symbol
Xport-Bprovided by FlyBase
Official Full Name
exit protein of rhodopsin and TRP Bprovided by FlyBase
Primary source
FLYBASE:FBgn0260234
Locus tag
Dmel_CG42508
See related
AllianceGenome:FB:FBgn0260234
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG42508; Dmel\CG42508; xport-B; XPORT-B
Summary
Enables protein folding chaperone and protein transporter activity. Involved in protein localization to plasma membrane; protein localization to rhabdomere; and protein transport. Located in subrhabdomeral cisterna. Is integral component of endoplasmic reticulum membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in Bolwig organ. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Xport-B in Genome Data Viewer
Location:
92B6-92B6; 3-67 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19914320..19915412, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15740042..15741134, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein at 92B Neighboring gene long non-coding RNA:CR45047 Neighboring gene long non-coding RNA:CR45048 Neighboring gene exit protein of rhodopsin and TRP A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TRP and Rhodopsin Transport Depends on Dual XPORT ER Chaperones Encoded by an Operon. Chen Z, et al. Cell Rep, 2015 Oct 20. PMID 26456832, Free PMC Article
  2. Membrane protein trafficking in Drosophila photoreceptor cells. Schopf K, et al. Eur J Cell Biol, 2017 Aug. PMID 27964885
  3. Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes. Takahashi H, et al. Sci Rep, 2020 Oct 1. PMID 33004976, Free PMC Article
  4. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
  5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein localization to rhabdomere IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of endoplasmic reticulum chaperone complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in subrhabdomeral cisterna IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
exit protein of rhodopsin and TRP B
Names
CG42508-PA
CG42508-PB
Xport-B-PA
Xport-B-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19914320..19915412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275820.2 → NP_001262749.1  exit protein of rhodopsin and TRP B, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262749.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIQ5

  2. NM_001170187.2 → NP_001163658.1  exit protein of rhodopsin and TRP B, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163658.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIQ5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
E1JIQ5 E1JIQ5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials