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uvrC excinuclease ABC subunit UvrC [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886672, updated on 6-Oct-2023

Summary

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Gene symbol
uvrC
Gene description
excinuclease ABC subunit UvrC
Locus tag
Rv1420
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (1594042..1595982)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene lipoprotein LprH Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator WhiA Neighboring gene membrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The intrinsic ATPase activity of Mycobacterium tuberculosis UvrC is crucial for its damage-specific DNA incision function.
    Title: The intrinsic ATPase activity of Mycobacterium tuberculosis UvrC is crucial for its damage-specific DNA incision function.
  2. Structural bioinformatics, homology modeling and molecular docking techniques were used to study UvrC protein from M. tuberculosis.
    Title: Homology modeling, molecular docking and DNA binding studies of nucleotide excision repair UvrC protein from M. tuberculosis.
  3. Data indicates a key functional role for UvrA in protection against reactive oxygen and nitrogen species-triggered DNA damage.
    Title: The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action.
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General gene information

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Homology

General protein information

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Preferred Names
excinuclease ABC subunit UvrC
NP_215936.1
  • nuclease UvrC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1594042..1595982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215936.1 excinuclease ABC subunit UvrC [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215936.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M7Z2
    Conserved Domains (1) summary
    PRK00558
    Location:4 → 640
    uvrC; excinuclease ABC subunit UvrC
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WFC5.1

Gene LinkOut

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Molecular Biology Databases