U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TEX30 testis expressed 30 [ Homo sapiens (human) ]

Gene ID: 93081, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
TEX30provided by HGNC
Official Full Name
testis expressed 30provided by HGNC
Primary source
HGNC:HGNC:25188
See related
Ensembl:ENSG00000151287 AllianceGenome:HGNC:25188
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C13orf27
Summary
Predicted to enable hydrolase activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 28.8), liver (RPKM 4.4) and 7 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
13q33.1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (102765888..102773786, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (101983926..101991831, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (103418238..103426136, complement)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene coiled-coil domain containing 168 Neighboring gene ReSE screen-validated silencer GRCh37_chr13:103407292-103407513 Neighboring gene uncharacterized LOC105370337 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:103425891-103426568 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:103426569-103427246 Neighboring gene protein O-glucosyltransferase 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7970 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5484 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5485 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5486 Neighboring gene BIVM-ERCC5 readthrough Neighboring gene basic, immunoglobulin-like variable motif containing Neighboring gene RNY5 pseudogene 8

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The DNA sequence and analysis of human chromosome 13. Dunham A, et al. Nature, 2004 Apr 1. PMID 15057823, Free PMC Article
  2. Large-scale concatenation cDNA sequencing. Yu W, et al. Genome Res, 1997 Apr. PMID 9110174, Free PMC Article
  3. A "double adaptor" method for improved shotgun library construction. Andersson B, et al. Anal Biochem, 1996 Apr 5. PMID 8619474
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. Suzuki Y, et al. Genome Res, 2004 Sep. PMID 15342556, Free PMC Article
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Lamesch P, et al. Genomics, 2007 Mar. PMID 17207965, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

General protein information

Go to the top of the page Help
Preferred Names
testis-expressed protein 30
Names
testis-expressed sequence 30 protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286775.2 → NP_001273704.1  testis-expressed protein 30 isoform 2

    See identical proteins and their annotated locations for NP_001273704.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    BC015148, BG527702, HY045638, HY229390
    Consensus CDS
    CCDS66578.1
    UniProtKB/Swiss-Prot
    Q5JUR7
    Related
    ENSP00000365197.3, ENST00000376029.3

  2. NM_001286776.2 → NP_001273705.1  testis-expressed protein 30 isoform 3

    See identical proteins and their annotated locations for NP_001273705.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus than isoform 1.
    Source sequence(s)
    BC015148, BI559423, HY229390
    Consensus CDS
    CCDS66577.1
    UniProtKB/TrEMBL
    A0A0C4DFW4, B2RC94
    Related
    ENSP00000365189.4, ENST00000376021.8
    Conserved Domains (1) summary
    cl21494
    Location:57 → 178
    Abhydrolase; alpha/beta hydrolases

  3. NM_138779.5 → NP_620134.3  testis-expressed protein 30 isoform 1

    See identical proteins and their annotated locations for NP_620134.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    BC015148, HY229390
    Consensus CDS
    CCDS9503.2
    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8
    UniProtKB/TrEMBL
    B2RC94
    Related
    ENSP00000365200.4, ENST00000376032.9
    Conserved Domains (1) summary
    cl21494
    Location:32 → 219
    Abhydrolase; alpha/beta hydrolases

RNA

  1. NR_104590.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two internal exons, compared to variant 1. This variant is represented as non-coding because the predicted ORF does not meet RefSeq quality criteria.
    Source sequence(s)
    BI861260, HY045638, HY229390

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    102765888..102773786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449439.2 → XP_024305207.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8
    UniProtKB/TrEMBL
    B2RC94
    Conserved Domains (1) summary
    cl21494
    Location:32 → 219
    Abhydrolase; alpha/beta hydrolases

  2. XM_005254097.4 → XP_005254154.1  testis-expressed protein 30 isoform X1

    See identical proteins and their annotated locations for XP_005254154.1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8
    UniProtKB/TrEMBL
    B2RC94
    Conserved Domains (1) summary
    cl21494
    Location:32 → 219
    Abhydrolase; alpha/beta hydrolases

  3. XM_047430773.1 → XP_047286729.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8

  4. XM_017020852.3 → XP_016876341.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8
    UniProtKB/TrEMBL
    B2RC94
    Conserved Domains (1) summary
    cl21494
    Location:32 → 219
    Abhydrolase; alpha/beta hydrolases

  5. XM_047430774.1 → XP_047286730.1  testis-expressed protein 30 isoform X3

  6. XM_011521136.3 → XP_011519438.1  testis-expressed protein 30 isoform X2

    Conserved Domains (1) summary
    cl21494
    Location:54 → 175
    Abhydrolase; alpha/beta hydrolases

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    101983926..101991831 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054375187.1 → XP_054231162.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8

  2. XM_054375185.1 → XP_054231160.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8

  3. XM_054375186.1 → XP_054231161.1  testis-expressed protein 30 isoform X1

    UniProtKB/Swiss-Prot
    Q5JUR7, Q5JUR8, Q96KZ8

  4. XM_054375189.1 → XP_054231164.1  testis-expressed protein 30 isoform X3

  5. XM_054375188.1 → XP_054231163.1  testis-expressed protein 30 isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5JUR7.1 GenPept UniProtKB/Swiss-Prot:Q5JUR7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous