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insB1 IS1 family protein InsB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944743, updated on 4-Apr-2024

Summary

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Gene symbol
insB1
Gene description
IS1 family protein InsB
Primary source
ASAP:ABE-0000075
Locus tag
b0021
See related
ECOCYC:G6085
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0022
Summary
IS1 is inserted in 7 locations in MG1655, designated IS1ABCDEFH; IS1G is specific to the W3110 K-12 chromosome. [More information is available at EcoGene: EG60002]. IS1 is the smallest insertion sequence in Escherichia coli. [More information is available at EcoCyc: G6085].
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Genomic context

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Sequence:
NC_000913.3 (19811..20314, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene Na(+):H(+) antiporter NhaA Neighboring gene DNA-binding transcriptional activator NhaR Neighboring gene IS1 family protein InsA Neighboring gene 30S ribosomal subunit protein S20 Neighboring gene DUF2575 domain-containing protein YaaY

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequence of an insertion element, IS1. Ohtsubo H, et al. Proc Natl Acad Sci U S A, 1978 Feb. PMID 273224, Free PMC Article
  2. Genetic analyses of the interactions of the IS1-encoded proteins with the left end of IS1 and its insertion hotspot. Matsutani S. J Mol Biol, 1997 Apr 4. PMID 9126837
  3. The insE open reading frame of IS1 is not required for formation of cointegrates. Freund ET, et al. J Bacteriol, 1996 Apr. PMID 8636048, Free PMC Article
  4. Frameshifting is required for production of the transposase encoded by insertion sequence 1. Sekine Y, et al. Proc Natl Acad Sci U S A, 1989 Jun. PMID 2543983, Free PMC Article
  5. Is the IS1 transposase, InsAB', the only IS1-encoded protein required for efficient transposition? Escoubas JM, et al. J Bacteriol, 1994 Sep. PMID 8083181, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transposase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA transposition IEA
Inferred from Electronic Annotation
more info
  
involved_in transposition IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
IS1 family protein InsB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    19811..20314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414562.1 IS1 family protein InsB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414562.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0CF31
    UniProtKB/TrEMBL
    A0A0A8J546, A0A2H4TP98
    Conserved Domains (1) summary
    cl00721
    Location:37 → 167
    DDE_Tnp_IS1; IS1 transposase
Nucleotide Protein
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