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rutR DNA-binding transcriptional dual regulator RutR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945075, updated on 4-Apr-2024

Summary

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Gene symbol
rutR
Gene description
DNA-binding transcriptional dual regulator RutR
Primary source
ASAP:ABE-0003422
Locus tag
b1013
See related
ECOCYC:EG12301
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1004; ycdC
Summary
RutR is also the global regulator of a pyrimidine metabolism regulon (Shimada, 2007). [More information is available at EcoGene: EG12301]. RutR regulates genes directly or indirectly involved in the complex pathway of pyrimidine metabolism and also plays a role in regulation of the genes for degradation of purines and genes for maintenance of pH homeostasis . [More information is available at EcoCyc: EG12301].
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Genomic context

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Sequence:
NC_000913.3 (1074242..1074880)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 3-aminoacrylate deaminase Neighboring gene ureidoacrylate amidohydrolase Neighboring gene pyrimidine monooxygenase RutA Neighboring gene fused DNA-binding transcriptional repressor/proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase PutA Neighboring gene protein YmdG

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The protein-DNA contacts in RutR•carAB operator complexes. Nguyen Ple M, et al. Nucleic Acids Res, 2010 Oct. PMID 20472642, Free PMC Article
  2. The Escherichia coli RutR transcription factor binds at targets within genes as well as intergenic regions. Shimada T, et al. Nucleic Acids Res, 2008 Jul. PMID 18515344, Free PMC Article
  3. The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines. Hasegawa A, et al. Microbiology (Reading), 2008 Nov. PMID 18957590
  4. Comparative genomics reveals novel biochemical pathways. Piskur J, et al. Trends Genet, 2007 Aug. PMID 17555842
  5. A hidden metabolic pathway exposed. Osterman A. Proc Natl Acad Sci U S A, 2006 Apr 11. PMID 16595627, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional dual regulator RutR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1074242..1074880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415533.1 DNA-binding transcriptional dual regulator RutR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415533.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A797I074
    Conserved Domains (1) summary
    PRK15008
    Location:1 → 212
    PRK15008; HTH-type transcriptional regulator RutR; Provisional
Nucleotide Protein
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