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purR DNA-binding transcriptional repressor PurR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945226, updated on 4-Apr-2024

Summary

Gene symbol
purR
Gene description
DNA-binding transcriptional repressor PurR
Primary source
ASAP:ABE-0005545
Locus tag
b1658
See related
ECOCYC:EG10800
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1654
Summary
The purine regulon includes purBCDEFHKLMN and guaBA. [More information is available at EcoGene: EG10800]. PurR is a protein that belongs to the GalR/LacI family. [More information is available at EcoCyc: EG10800].
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Genomic context

Sequence:
NC_000913.3 (1737844..1738869)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YdhP Neighboring gene cytochrome bd-I accessory subunit CydH Neighboring gene DNA-binding transcriptional activator PunR Neighboring gene purine nucleoside transporter PunC Neighboring gene cyclopropane fatty acyl phospholipid synthase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription repressor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables guanine binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA-binding transcriptional repressor PurR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1737844..1738869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416175.1 DNA-binding transcriptional repressor PurR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416175.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377K5U0
    Conserved Domains (1) summary
    PRK10703
    Location:1341
    PRK10703; HTH-type transcriptional repressor PurR