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tmk hypothetical protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945663, updated on 30-May-2019

Summary

Gene symbol
tmk
Gene description
hypothetical protein
Primary source
EcoGene:EG12302
Locus tag
b1098
See related
ASAP:ABE-0003714; ECOCYC:EG12302
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1084; ycfG
Summary
Essential gene. [More information is available at EcoGene: EG12302]. The enzyme is responsible for specifically catalyzing the conversion of dTMP to dTDP. dTMP kinase is the last unique enzyme in the pathway leading to dTTP. [More information is available at EcoCyc: EG12302].

Genomic context

Sequence:
NC_000913.3 (1155124..1155765)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene beta-ketoacyl-[acyl carrier protein] synthase II Neighboring gene aminodeoxychorismate lyase Neighboring gene endolytic murein transglycosylase Neighboring gene DNA polymerase III subunit delta' Neighboring gene putative metal-dependent hydrolase YcfH Neighboring gene glucose-specific PTS enzyme IIBC component

Pathways from BioSystems

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
thymidylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
thymidylate kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
uridylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
dTDP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dTDP biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
dTTP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dTTP biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
dTTP biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
dUDP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleobase-containing small molecule interconversion IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
hypothetical protein
NP_415616.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1155124..1155765
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415616.1 hypothetical protein b1098 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415616.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A720
    Conserved Domains (1) summary
    PRK00698
    Location:1209
    tmk; thymidylate kinase; Validated
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