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tynA copper-containing amine oxidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945939, updated on 30-May-2019

Summary

Gene symbol
tynA
Gene description
copper-containing amine oxidase
Primary source
EcoGene:EG13139
Locus tag
b1386
See related
ASAP:ABE-0004639; ECOCYC:EG13139
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1383; feaA; maoA
Summary
Topaquinone (TPQ) is 2,4,5-trihydroxyphenylalanine quinone, and is derived from a tyrosyl residue in the active site, in a copper-dependent oxidation reaction. [More information is available at EcoGene: EG13140].

Genomic context

Sequence:
NC_000913.3 (1449076..1451349, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator FeaR Neighboring gene phenylacetaldehyde dehydrogenase Neighboring gene oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase Neighboring gene phenylacetyl-CoA 1,2-epoxidase, monooxygenase subunit

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
copper ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
copper ion binding IDA
Inferred from Direct Assay
more info
PubMed 
primary amine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
primary amine oxidase activity IDA
Inferred from Direct Assay
more info
PubMed 
quinone binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
amine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
phenylethylamine catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
phenylethylamine catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
copper-containing amine oxidase
NP_415904.3

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1449076..1451349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415904.3 copper-containing amine oxidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415904.3

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P46883
    Conserved Domains (1) summary
    PRK14696
    Location:37757
    tynA; tyramine oxidase; Provisional
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