U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

wcaI colanic acid biosynthesis fucosyltransferase WcaI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946588, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
wcaI
Gene description
colanic acid biosynthesis fucosyltransferase WcaI
Primary source
ASAP:ABE-0006794
Locus tag
b2050
See related
ECOCYC:EG11790
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2044; yefD
Summary
WcaI is believed to be a glycosyl transferase involved in colanic acid synthesis based on sequence similarity and its presence in a putative colanic acid synthesis operon . [More information is available at EcoCyc: EG11790].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (2124523..2125746, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphomannomutase Neighboring gene mannose-1-phosphate guanylyltransferase Neighboring gene GDP-mannose mannosyl hydrolase Neighboring gene GDP-L-fucose synthase Neighboring gene GDP-mannose 4,6-dehydratase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Evidence for effect of random genetic drift on G+C content after lateral transfer of fucose pathway genes to Escherichia coli K-12. Aoyama K, et al. Mol Biol Evol, 1994 Nov. PMID 7815923
  2. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
  3. Development of a biofilm production-deficient Escherichia coli strain as a host for biotechnological applications. Sung BH, et al. Appl Environ Microbiol, 2006 May. PMID 16672475, Free PMC Article
  4. Genome-wide analyses revealing a signaling network of the RcsC-YojN-RcsB phosphorelay system in Escherichia coli. Hagiwara D, et al. J Bacteriol, 2003 Oct. PMID 13129944, Free PMC Article
  5. Identification of the Functional Roles of Six Key Proteins in the Biosynthesis of Enterobacteriaceae Colanic Acid. Scott PM, et al. Biochemistry, 2019 Apr 2. PMID 30821147, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-(1->3)-fucosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within colanic acid biosynthetic process IGC
Inferred from Genomic Context
more info
 PubMed 
involved_in lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in slime layer polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
colanic acid biosynthesis fucosyltransferase WcaI

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2124523..2125746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416554.1 colanic acid biosynthesis fucosyltransferase WcaI [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416554.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7RYG2
    Conserved Domains (1) summary
    TIGR04007
    Location:1 → 407
    wcaI; colanic acid biosynthesis glycosyl transferase WcaI
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.