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tolA Tol-Pal system protein TolA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946625, updated on 30-May-2019

Summary

Gene symbol
tolA
Gene description
Tol-Pal system protein TolA
Primary source
EcoGene:EG11007
Locus tag
b0739
See related
ASAP:ABE-0002515; ECOCYC:EG11007
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cim; ECK0728; excC; lky; tol-2
Summary
Cell envelope integrity is stabilized by the Tol-Pal system linking inner and outer membranes. [More information is available at EcoGene: EG11007]. TolA is one of three (along with TolQ and TolR) inner membrane protein members of the YbgC-YbgF-TolQ-R-A-B-Pal Cell Envelope Complex, also known as the Tol-Pal system. [More information is available at EcoCyc: EG11007].

Genomic context

Sequence:
NC_000913.3 (776342..777607)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene esterase/thioesterase Neighboring gene Tol-Pal system protein TolQ Neighboring gene Tol-Pal system protein TolR Neighboring gene Tol-Pal system periplasmic protein TolB Neighboring gene peptidoglycan-associated outer membrane lipoprotein Pal

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
disordered domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
virion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
bacteriocin transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell division IDA
Inferred from Direct Assay
more info
PubMed 
cell division IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to bacteriocin IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein import IMP
Inferred from Mutant Phenotype
more info
PubMed 
viral entry into host cell IDA
Inferred from Direct Assay
more info
PubMed 
viral entry into host cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell division site IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Tol-Pal system protein TolA

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    776342..777607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415267.1 Tol-Pal system protein TolA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415267.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P19934
    Conserved Domains (1) summary
    PRK09510
    Location:1421
    tolA; cell envelope integrity inner membrane protein TolA; Provisional
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