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hisS histidine--tRNA ligase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946989, updated on 11-Oct-2018

Summary

Gene symbol
hisS
Gene description
histidine--tRNA ligase
Primary source
EcoGene:EG10453
Locus tag
b2514
See related
ASAP:ABE-0008278; ECOCYC:EG10453
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2510
Summary
Histidyl-tRNA synthetase (HisRS) is a member of the family of aminoacyl-tRNA synthetases, which interpret the genetic code by covalently linking amino acids to their specific tRNA molecules. [More information is available at EcoCyc: EG10453].

Genomic context

Sequence:
NC_000913.3 (2639301..2640575, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane protein assembly factor BamB Neighboring gene ancillary SecYEG translocon subunit Neighboring gene (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) Neighboring gene transmembrane component of cytoskeleton

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
histidine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histidine-tRNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
histidyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histidyl-tRNA aminoacylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
histidine--tRNA ligase
NP_417009.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2639301..2640575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417009.1 histidine--tRNA ligase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417009.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P60906
    Conserved Domains (1) summary
    PRK00037
    Location:4424
    hisS; histidyl-tRNA synthetase; Reviewed
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