Format

Send to:

Choose Destination

mltB membrane-bound lytic murein transglycosylase B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947184, updated on 7-Jul-2019

Summary

Gene symbol
mltB
Gene description
membrane-bound lytic murein transglycosylase B
Primary source
EcoGene:EG12699
Locus tag
b2701
See related
ASAP:ABE-0008885; ECOCYC:G7410
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2696; slt
Summary
MltB cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. [More information is available at EcoGene: EG12699]. MltB is one of six (along with MltA, MltC, MltD, EmtA, and Slt70) major lytic endotransglycosylases expressed in Escherichia coli. [More information is available at EcoCyc: G7410].

Genomic context

Sequence:
NC_000913.3 (2824491..2825576, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA recombination/repair protein RecA Neighboring gene NMN aminohydrolase Neighboring gene sorbitol-specific PTS enzyme IIC2 component Neighboring gene sorbitol-specific PTS enzyme IIBC1 component Neighboring gene sorbitol-specific PTS enzyme IIA component

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
lytic endotransglycosylase activity IDA
Inferred from Direct Assay
more info
PubMed 
lytic transglycosylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lytic transglycosylase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sodium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
peptidoglycan catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
peptidoglycan catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cell outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
outer membrane-bounded periplasmic space TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
membrane-bound lytic murein transglycosylase B
NP_417181.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2824491..2825576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417181.1 membrane-bound lytic murein transglycosylase B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417181.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P41052
    Conserved Domains (1) summary
    PRK10760
    Location:1361
    PRK10760; murein hydrolase B; Provisional
Support Center