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hemC hydroxymethylbilane synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947759, updated on 30-May-2019

Summary

Gene symbol
hemC
Gene description
hydroxymethylbilane synthase
Primary source
EcoGene:EG10429
Locus tag
b3805
See related
ASAP:ABE-0012427; ECOCYC:EG10429
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3799; popE

Genomic context

Sequence:
NC_000913.3 (3989825..3990766, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein HemY Neighboring gene PF04375 family protein HemX Neighboring gene uroporphyrinogen-III synthase Neighboring gene adenylate cyclase Neighboring gene frataxin CyaY Neighboring gene protein YzcX

Pathways from BioSystems

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
hydroxymethylbilane synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydroxymethylbilane synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
hydroxymethylbilane synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
heme biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heme biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
peptidyl-pyrromethane cofactor linkage IDA
Inferred from Direct Assay
more info
PubMed 
protoporphyrinogen IX biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
tetrapyrrole biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
hydroxymethylbilane synthase
YP_026260.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3989825..3990766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026260.1 hydroxymethylbilane synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026260.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P06983
    Conserved Domains (1) summary
    PRK00072
    Location:4296
    hemC; porphobilinogen deaminase; Reviewed
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